Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2592744..2592928 Replicon chromosome
Accession NC_009487
Organism Staphylococcus aureus subsp. aureus JH9

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag SAURJH9_RS13360 Protein ID WP_000482652.1
Coordinates 2592821..2592928 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2592744..2592804 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAURJH9_RS13335 2588199..2588366 - 168 Protein_2536 hypothetical protein -
SAURJH9_RS13345 2588597..2590330 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
SAURJH9_RS13350 2590355..2592118 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2592744..2592804 + 61 - - Antitoxin
SAURJH9_RS13360 2592821..2592928 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
SAURJH9_RS13365 2593062..2593448 - 387 WP_000779360.1 flippase GtxA -
SAURJH9_RS13370 2593716..2594858 + 1143 WP_001176863.1 glycerate kinase -
SAURJH9_RS13375 2594918..2595577 + 660 WP_000831298.1 membrane protein -
SAURJH9_RS13380 2595759..2596970 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAURJH9_RS13385 2597093..2597566 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T22125 WP_000482652.1 NC_009487:c2592928-2592821 [Staphylococcus aureus subsp. aureus JH9]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T22125 NC_009487:c2592928-2592821 [Staphylococcus aureus subsp. aureus JH9]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT22125 NC_009487:2592744-2592804 [Staphylococcus aureus subsp. aureus JH9]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References