Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2306167..2306383 Replicon chromosome
Accession NC_009487
Organism Staphylococcus aureus subsp. aureus JH9

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAURJH9_RS11845 Protein ID WP_001802298.1
Coordinates 2306279..2306383 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2306167..2306222 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAURJH9_RS11825 2302373..2303038 - 666 WP_001024095.1 SDR family oxidoreductase -
SAURJH9_RS11830 2303190..2303510 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAURJH9_RS11835 2303512..2304489 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
SAURJH9_RS11840 2304755..2305846 + 1092 WP_000495669.1 hypothetical protein -
- 2306167..2306222 + 56 - - Antitoxin
SAURJH9_RS11845 2306279..2306383 - 105 WP_001802298.1 hypothetical protein Toxin
SAURJH9_RS15615 2307063..2307221 + 159 WP_001792784.1 hypothetical protein -
SAURJH9_RS11850 2307879..2308736 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
SAURJH9_RS11855 2308804..2309586 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T22123 WP_001802298.1 NC_009487:c2306383-2306279 [Staphylococcus aureus subsp. aureus JH9]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T22123 NC_009487:c2306383-2306279 [Staphylococcus aureus subsp. aureus JH9]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT22123 NC_009487:2306167-2306222 [Staphylococcus aureus subsp. aureus JH9]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References