Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 4248556..4249213 Replicon chromosome
Accession NZ_CP085627
Organism Erwinia rhapontici strain BY21311

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LJN55_RS19590 Protein ID WP_133842340.1
Coordinates 4248556..4248891 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LJN55_RS19595 Protein ID WP_159336876.1
Coordinates 4248896..4249213 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJN55_RS19570 (LJN55_19570) 4244120..4245043 - 924 WP_227535086.1 sugar ABC transporter permease -
LJN55_RS19575 (LJN55_19575) 4245109..4246395 - 1287 WP_227535087.1 sugar ABC transporter substrate-binding protein -
LJN55_RS19580 (LJN55_19580) 4246418..4247575 - 1158 WP_227535089.1 PLP-dependent transferase -
LJN55_RS19585 (LJN55_19585) 4247556..4248275 - 720 WP_133842339.1 FadR/GntR family transcriptional regulator -
LJN55_RS19590 (LJN55_19590) 4248556..4248891 + 336 WP_133842340.1 toxin Toxin
LJN55_RS19595 (LJN55_19595) 4248896..4249213 + 318 WP_159336876.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LJN55_RS19600 (LJN55_19600) 4249288..4250031 - 744 WP_212813282.1 phosphatase PAP2 family protein -
LJN55_RS19605 (LJN55_19605) 4250237..4253461 - 3225 WP_133842343.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-88)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12589.37 Da        Isoelectric Point: 9.5577

>T220977 WP_133842340.1 NZ_CP085627:4248556-4248891 [Erwinia rhapontici]
VDAIFIELPPFARHRVDYFSDDAFRSLQNLLMLCPTCGDVIQHTGGLRKLRVGDAHRHKGKRGGSRVIYYWWQEQAHFLL
FTVYSKGEASDLSPAQRDSLRSLLANLTKGG

Download         Length: 336 bp

>T220977 NZ_CP117322:3393406-3393624 [Salmonella enterica subsp. enterica serovar Derby]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAACTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12021.85 Da        Isoelectric Point: 8.5315

>AT220977 WP_159336876.1 NZ_CP085627:4248896-4249213 [Erwinia rhapontici]
MEKRDLYHELVEGFTALAEHHQGKKTLKTHRLAAKAEVVLAPEELRTIRENLQLSQAVFAQYLQTGLTTYQNWEQGRAKP
NKQAILLIRLIENESTTLEILAKLA

Download         Length: 318 bp

>AT220977 NZ_CP117322:3393004-3393378 [Salmonella enterica subsp. enterica serovar Derby]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGGTTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References