Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1534607..1535331 Replicon chromosome
Accession NC_009483
Organism Geobacter uraniireducens Rf4

Toxin (Protein)


Gene name mqsR Uniprot ID A5GA92
Locus tag GURA_RS06615 Protein ID WP_011938218.1
Coordinates 1534607..1534906 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag GURA_RS23300 Protein ID WP_011938219.1
Coordinates 1534909..1535331 (+) Length 141 a.a.

Genomic Context

GURA_RS06600GURA_RS06605GURA_RS06615GURA_RS23300GURA_RS06625GURA_RS06610GURA_RS06630GURA_RS06635
Location: 1530707..1531042 (336 bp)
Type: Others
Protein ID: WP_011938215.1
Location: 1531072..1532631 (1560 bp)
Type: Others
Protein ID: WP_198134532.1
Location: 1534607..1534906 (300 bp)
Type: Toxin
Protein ID: WP_011938218.1
Location: 1534909..1535331 (423 bp)
Type: Antitoxin
Protein ID: WP_011938219.1
Location: 1535762..1537099 (1338 bp)
Type: Others
Protein ID: WP_011938221.1
Location: 1532734..1534452 (1719 bp)
Type: Others
Protein ID: WP_041245801.1
Location: 1537395..1537664 (270 bp)
Type: Others
Protein ID: WP_011938222.1
Location: 1537927..1538202 (276 bp)
Type: Others
Protein ID: WP_011938223.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GURA_RS066001530707..1531042+336WP_011938215.1DUF1622 domain-containing protein-
GURA_RS066051531072..1532631+1560WP_198134532.1efflux transporter outer membrane subunit-
GURA_RS066101532734..1534452-1719WP_041245801.1B12-binding domain-containing radical SAM protein-
GURA_RS066151534607..1534906+300WP_011938218.1type II toxin-antitoxin system MqsR family toxinToxin
GURA_RS233001534909..1535331+423WP_011938219.1type II toxin-antitoxin system MqsA family antitoxinAntitoxin
GURA_RS066251535762..1537099+1338WP_011938221.1radical SAM protein-
GURA_RS066301537395..1537664-270WP_011938222.1hypothetical protein-
GURA_RS066351537927..1538202-276WP_011938223.1acylphosphatase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Zinc finger, MqsA-type

(10-53)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11662.64 Da        Isoelectric Point: 10.0311

>T22094 WP_011938218.1 NC_009483:1534607-1534906 [Geobacter uraniireducens Rf4]
MEKRRPHYDLKSIQAQMDCIEAMNLTMTARHGIKAIGMALGDALVVIKRLSMGNFYKAMTVHADSRVWQDVYHAEWKGRA
LYIKFQRHEEFFIVSFKER

Download         Length: 300 bp

>T22094 NC_009483:1534607-1534906 [Geobacter uraniireducens Rf4]
ATGGAAAAGCGACGTCCCCATTATGACCTCAAGTCGATCCAGGCACAGATGGACTGCATTGAGGCAATGAACCTGACCAT
GACCGCCCGACACGGCATCAAAGCGATCGGAATGGCCTTGGGAGATGCGCTGGTGGTAATCAAGAGGCTTTCAATGGGAA
ATTTTTATAAGGCCATGACAGTTCATGCGGACAGCAGGGTTTGGCAAGATGTATATCACGCTGAATGGAAAGGAAGGGCC
TTGTACATCAAGTTTCAGCGACACGAAGAATTCTTTATCGTGTCGTTCAAGGAGCGTTGA

Antitoxin


Download         Length: 141 a.a.        Molecular weight: 15623.75 Da        Isoelectric Point: 8.1333

>AT22094 WP_011938219.1 NC_009483:1534909-1535331 [Geobacter uraniireducens Rf4]
MSKQWNGKTCPACFQGTLEHRVKRTQFEYRSNILEYDQEGAWCGTCGEGIVTGKEAAAAESLLDDFIARVDKEEASELAR
IRKKLGLNQKEAAMIAGGGHNAFSRYERGEARPVAAVVNLFRLLDRHPELLNELKKQKAA

Download         Length: 423 bp

>AT22094 NC_009483:1534909-1535331 [Geobacter uraniireducens Rf4]
ATGAGTAAACAATGGAACGGGAAAACATGTCCCGCATGTTTTCAGGGAACTTTGGAACATCGGGTGAAACGGACGCAATT
TGAGTACCGCAGCAACATTCTGGAATACGACCAGGAAGGGGCTTGGTGCGGCACATGTGGTGAAGGGATCGTCACTGGAA
AAGAAGCGGCTGCCGCTGAATCGTTGCTTGACGATTTCATTGCCCGTGTGGACAAGGAAGAGGCTTCCGAACTGGCCCGC
ATCAGAAAGAAGCTCGGACTTAACCAGAAGGAGGCGGCCATGATCGCCGGTGGCGGCCACAACGCCTTCTCTCGCTACGA
GAGGGGTGAAGCCAGACCCGTTGCCGCTGTAGTGAACCTCTTCCGTCTGCTGGACCGGCATCCTGAGCTGCTGAACGAAT
TGAAAAAGCAAAAAGCCGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA5GA92

Antitoxin

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Source
ID
Structure
No matching records found

References