Detailed information of TA system TA220713

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 802086..802280
• Replicon: chromosome
• Accession: NZ_CP085294
• Organism: Enterococcus faecalis strain EFS108

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LIT97_RS03800
• Protein ID: WP_015543884.1
• Coordinates: 802185..802280 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	802086..802150 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LIT97_RS03785	797717..799459	+	1743	WP_002392494.1	PTS transporter subunit EIIC	-
LIT97_RS03790	799450..801483	+	2034	WP_002355275.1	BglG family transcription antiterminator	-
LIT97_RS03795	801494..801928	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	802086..802150	+	65	-	-	Antitoxin
LIT97_RS03800	802185..802280	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LIT97_RS03805	802526..804298	+	1773	WP_002391520.1	PTS mannitol-specific transporter subunit IIBC	-
LIT97_RS03810	804313..804750	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LIT97_RS03815	804765..805919	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
LIT97_RS03820	805988..807103	-	1116	WP_002364956.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T220713 WP_015543884.1 NZ_CP085294:c802280-802185 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T220713 NZ_CP117255:c2076364-2076101 [Rhizobium tumorigenes]
ATGGCTTTTGAGTTTGATCCCGACAAAAGCAGAACAAACAAAATCAAGCATGGTATTGATCTTGTGGAGGCGCAGCGTCT
TTGGATCGATCGCTTTTTGATTTCATTCCCCGCTCGGGACGGACTTGAAAGCCGGTTTGTCGCGATCGGTCAAATAGACG
GGAAGCACTGGTCCGCGATTTGCACGAGACGTCATGACAATATCAGGATCATTTCGGTTCGCAGGTCGAGGAAAGAGGAG
ATAGCTCTCTATGAAGGCAAGTGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT220713 NZ_CP085294:802086-802150 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTT

Structures

Antitoxin