Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 1004966..1005161 Replicon chromosome
Accession NZ_CP085291
Organism Enterococcus faecalis strain EFS36

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag LIT96_RS04890 Protein ID WP_015543884.1
Coordinates 1004966..1005061 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 1005096..1005161 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LIT96_RS04870 1000145..1001260 + 1116 WP_002361174.1 FAD-dependent oxidoreductase -
LIT96_RS04875 1001327..1002481 - 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
LIT96_RS04880 1002496..1002933 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
LIT96_RS04885 1002948..1004720 - 1773 WP_010717458.1 PTS mannitol-specific transporter subunit IIBC -
LIT96_RS04890 1004966..1005061 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1005096..1005161 - 66 - - Antitoxin
LIT96_RS04895 1005319..1005753 - 435 WP_002355276.1 PTS sugar transporter subunit IIA -
LIT96_RS04900 1005764..1007797 - 2034 WP_002370205.1 PRD domain-containing protein -
LIT96_RS04905 1007788..1009530 - 1743 WP_002403026.1 PTS transporter subunit EIIC -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T220670 WP_015543884.1 NZ_CP085291:1004966-1005061 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T220670 NZ_CP117238:c808690-808502 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 66 bp

>AT220670 NZ_CP085291:c1005161-1005096 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References