Detailed information of TA system TA220657

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 1468866..1469061
• Replicon: chromosome
• Accession: NZ_CP085289
• Organism: Enterococcus faecalis strain EFS17

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LIT95_RS07075
• Protein ID: WP_015543884.1
• Coordinates: 1468966..1469061 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	1468866..1468931 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LIT95_RS07060	1464497..1466239	+	1743	WP_002403026.1	PTS transporter subunit EIIC	-
LIT95_RS07065	1466230..1468263	+	2034	WP_002370205.1	PRD domain-containing protein	-
LIT95_RS07070	1468274..1468708	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	1468866..1468931	+	66	-	-	Antitoxin
LIT95_RS07075	1468966..1469061	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LIT95_RS07080	1469307..1471079	+	1773	WP_010717458.1	PTS mannitol-specific transporter subunit IIBC	-
LIT95_RS07085	1471094..1471531	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LIT95_RS07090	1471546..1472700	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
LIT95_RS07095	1472767..1473882	-	1116	WP_002361174.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T220657 WP_015543884.1 NZ_CP085289:c1469061-1468966 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T220657 NZ_CP117235:2595099-2595377 [Escherichia coli]
ATGATAATGAATTTCAGACACAAGGGATTGCGTGACTTGTTTCTTCTCGGCAAAACCTCCGGCGTTATACCGACGCAAGT
CAAACGATTACGCCACCGACTCGCTGTGATTGATGCAGCATGCTGTCTTGCTGATATCGATATGCCCGGTTACCGACTAC
ATCCGTTAAGCGGCGATCGCGATGGAATTTGGGCGATATCTGTCTCGGGTAACTGGCGAATCACATTTGAATTCGTCAAT
GGCGATGCATACATACTGGATTACGAGGACTATCACTGA

Antitoxin

Nucleotide

• Length: 66 bp

>AT220657 NZ_CP085289:1468866-1468931 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin