Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3703400..3703902 Replicon chromosome
Accession NZ_CP085032
Organism Proteus terrae subsp. cibarius strain ZJ19PC

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LHA39_RS16985 Protein ID WP_075671248.1
Coordinates 3703648..3703902 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LHA39_RS16980 Protein ID WP_072068851.1
Coordinates 3703400..3703651 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHA39_RS16955 (LHA39_16955) 3698991..3699767 + 777 WP_006534565.1 phosphate ABC transporter ATP-binding protein PstB -
LHA39_RS16960 (LHA39_16960) 3699782..3700516 + 735 WP_075671254.1 phosphate signaling complex protein PhoU -
LHA39_RS16965 (LHA39_16965) 3700732..3701571 + 840 WP_036933789.1 ABC transporter substrate-binding protein -
LHA39_RS16970 (LHA39_16970) 3701678..3702415 + 738 WP_075671252.1 amino acid ABC transporter permease -
LHA39_RS16975 (LHA39_16975) 3702417..3703169 + 753 WP_159242128.1 amino acid ABC transporter permease -
LHA39_RS16980 (LHA39_16980) 3703400..3703651 + 252 WP_072068851.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
LHA39_RS16985 (LHA39_16985) 3703648..3703902 + 255 WP_075671248.1 Txe/YoeB family addiction module toxin Toxin
LHA39_RS16990 (LHA39_16990) 3704059..3705417 + 1359 WP_075671246.1 NCS2 family permease -
LHA39_RS16995 (LHA39_16995) 3705498..3705809 + 312 WP_075671244.1 monooxygenase -
LHA39_RS17000 (LHA39_17000) 3705859..3706407 - 549 WP_075671242.1 GNAT family N-acetyltransferase -
LHA39_RS17005 (LHA39_17005) 3706410..3707882 - 1473 WP_075671240.1 glycosyltransferase family 39 protein -
LHA39_RS17010 (LHA39_17010) 3708071..3708568 + 498 WP_075671238.1 Der GTPase-activating protein YihI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10170.78 Da        Isoelectric Point: 9.9411

>T220222 WP_075671248.1 NZ_CP085032:3703648-3703902 [Proteus terrae subsp. cibarius]
MKLIFSEQSWSDYLYWQQIDKKIIKRINELIKDIKRTPFSGIGKPEPLKHNLAGFWSRRITDEHRLIYRITDSAIEIASC
RYHY

Download         Length: 255 bp

>T220222 NZ_CP116983:c70141-69761 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAACCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGATATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACTGCGCTAAACAGTGCG
CTGCTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACTGTAGGCGCTGCAACTGG
CGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9463.77 Da        Isoelectric Point: 4.4354

>AT220222 WP_072068851.1 NZ_CP085032:3703400-3703651 [Proteus terrae subsp. cibarius]
MKTINYTEARQNLTSIMNETIDDRVPIMITRQKGIPCVLLSLDEYQALEETAYLLRSPANARHLLDSIDELNQGKGIEKD
ITE

Download         Length: 252 bp

>AT220222 NZ_CP116983:c70362-70141 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAGGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References