Detailed information of TA system TA219803

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2343282..2343508
• Replicon: chromosome
• Accession: NZ_CP084892
• Organism: Staphylococcus aureus strain CC1956/ST4614-MSSA

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: LB315_RS11795
• Protein ID: WP_229373886.1
• Coordinates: 2343404..2343508 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2343282..2343375 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LB315_RS11750 (2338426)	2338426..2338677	+	252	WP_001566779.1	hypothetical protein	-
LB315_RS11755 (2338669)	2338669..2339433	-	765	WP_000600967.1	VOC family protein	-
LB315_RS11760 (2339596)	2339596..2340036	+	441	WP_000951062.1	winged helix DNA-binding protein	-
LB315_RS11765 (2340029)	2340029..2340316	+	288	Protein_2273	MFS transporter	-
LB315_RS11770 (2340832)	2340832..2341266	-	435	WP_229373883.1	chemotaxis protein	-
LB315_RS11775 (2341574)	2341574..2342068	-	495	WP_229373884.1	staphylokinase domain-containing protein	-
LB315_RS11780 (2342177)	2342177..2342932	-	756	WP_229373885.1	CHAP domain-containing protein	-
LB315_RS11785 (2342944)	2342944..2343201	-	258	WP_115211003.1	phage holin	-
LB315_RS11790 (2343253)	2343253..2343348	+	96	Protein_2278	hypothetical protein	-
- (2343282)	2343282..2343375	+	94	NuclAT_1	-	Antitoxin
- (2343282)	2343282..2343375	+	94	NuclAT_1	-	Antitoxin
- (2343282)	2343282..2343375	+	94	NuclAT_1	-	Antitoxin
- (2343282)	2343282..2343375	+	94	NuclAT_1	-	Antitoxin
LB315_RS11795 (2343404)	2343404..2343508	-	105	WP_229373886.1	hypothetical protein	Toxin
LB315_RS11800 (2343713)	2343713..2344012	-	300	WP_031797127.1	DUF2951 family protein	-
LB315_RS11805 (2344058)	2344058..2344222	-	165	WP_000916020.1	XkdX family protein	-
LB315_RS11810 (2344215)	2344215..2344604	-	390	WP_229373887.1	DUF2977 domain-containing protein	-
LB315_RS11815 (2344604)	2344604..2346070	-	1467	WP_229373888.1	BppU family phage baseplate upper protein	-
LB315_RS11820 (2346070)	2346070..2347980	-	1911	WP_229373889.1	hypothetical protein	-
LB315_RS11825 (2347996)	2347996..2348286	-	291	WP_000179864.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2340832..2386591	45759

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3917.74 Da
• Isoelectric Point: 5.5724

>T219803 WP_229373886.1 NZ_CP084892:c2343508-2343404 [Staphylococcus aureus]
MLLLERTSVSDFEMLMVVLTIISLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T219803 NZ_CP116718:3544283-3544858 [Pseudomonas aeruginosa]
ATGAGGCATTCCCCATTCACCGCCGTCTACGACGCGTGCGTTCTATATCCCGCGCCACTGCGGGATTTCCTGATGTGGCT
CGGCCTGTCTGGCCGCTTCCGGGCGCGGTGGAGCCAAGCCATTCATGAGGAGTGGAAACGCAACCTGTTGATCAACCGCC
CCGATCTCACCCGGGTTCAGGTCGACAGGACGTCGGATCTCATGGACAGGGCCATTCCGGACGGCTTGGTGGAGGGCTAC
GAAGCGCTCGTGGCAGGCCTGACATTACCCGATCCGAATGATCGGCACGTCCTGGCTGCGGCGATTCGCTGCGGTGCGAG
CGTGATTGTGACGTTCAACGAACGTGATTTCCCGAACGATCTGCTGGCTCCGTACGGCATCGAATCGCAGCACCCCGATG
AGTTTGTGGACAACCTGCTGGATCTGGATGCGGCCGCCGTAGTGTCGGCTGCGCAGCGCCAGCGTGCCCAACTCAAGCAT
CCGCCGATCGATGTGGACCGCTATCTCGAAATCCTGCTGCGCCAAGGCCTTGTGCAAACGACCAAGGTGCTGGCGACCTA
TCGCACCATTCTCTGA

Antitoxin

Nucleotide

• Length: 94 bp

>AT219803 NZ_CP084892:2343282-2343375 [Staphylococcus aureus]
ATAAATAGAAAAAGGGCAACATGCGCTAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTTTTCATAGAAAAA
TTATAAAAATAACC

Structures

Antitoxin