Detailed information of TA system TA219796

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 360895..361152
• Replicon: chromosome
• Accession: NZ_CP084892
• Organism: Staphylococcus aureus strain CC1956/ST4614-MSSA

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: LB315_RS01660
• Protein ID: WP_000253687.1
• Coordinates: 360895..361002 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	360992..361152 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LB315_RS01640	356056..359736	+	3681	WP_229374176.1	phage tail spike protein	-
LB315_RS01645	359723..359875	+	153	WP_229374177.1	hypothetical protein	-
LB315_RS01650	359922..360209	+	288	WP_229374179.1	hypothetical protein	-
LB315_RS01655	360304..360672	+	369	WP_229374782.1	hypothetical protein	-
LB315_RS01660	360895..361002	+	108	WP_000253687.1	putative holin-like toxin	Toxin
-	360992..361152	-	161	-	-	Antitoxin
LB315_RS01670	361202..361456	+	255	WP_229374181.1	phage holin	-
LB315_RS01675	361468..362223	+	756	WP_229374183.1	CHAP domain-containing protein	-
LB315_RS01680	362999..363330	+	332	Protein_334	SH3 domain-containing protein	-
LB315_RS01685	363719..364657	+	939	WP_229374185.1	leukocidin/hemolysin toxin family protein	-
LB315_RS01690	364653..365636	+	984	WP_229374783.1	Panton-Valentine bi-component leukocidin subunit F	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukS-PV / lukF-PV	322629..365636	43007

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3844.80 Da
• Isoelectric Point: 10.4997

>T219796 WP_000253687.1 NZ_CP084892:360895-361002 [Staphylococcus aureus]
VVSIVDALNLMFSFGMFIVTLLGLVIAIVKLNHKK

Nucleotide

• Length: 108 bp

>T219796 NZ_CP116717:4120798-4121376 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTTTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTTCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAAGCGGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCATCTGGACAC
GCCGCTGCGCGATCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGACCGCCGAAGCCCTGGCAGTGAAAGCGC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin

Nucleotide

• Length: 161 bp

>AT219796 NZ_CP084892:c361152-360992 [Staphylococcus aureus]
ATTTGATATTTATATTATGATGTGTTAATTTATATATAGAAAAAGGGCAACATGCGGAAACATGTCACCCTAGTGAGCCC
GTTAAAAAGACGGTGACCTCTTTTATATGATTAATAAATAACCATCAAAACCGGTCAAAGTTAGTGATGGTTATTTTTTA
T

Structures

Antitoxin