Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
| Location | 809377..809557 | Replicon | chromosome |
| Accession | NZ_CP084878 | ||
| Organism | Staphylococcus aureus strain GS426 | ||
Toxin (Protein)
| Gene name | sprA1 | Uniprot ID | - |
| Locus tag | LD199_RS04050 | Protein ID | WP_001801861.1 |
| Coordinates | 809462..809557 (-) | Length | 32 a.a. |
Antitoxin (RNA)
| Gene name | sprA1AS | ||
| Locus tag | - | ||
| Coordinates | 809377..809434 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LD199_RS04020 (LD199_04020) | 805087..805221 | + | 135 | WP_001791797.1 | hypothetical protein | - |
| LD199_RS04025 (LD199_04025) | 805385..806941 | + | 1557 | WP_000028669.1 | type I restriction-modification system subunit M | - |
| LD199_RS04030 (LD199_04030) | 806934..808162 | + | 1229 | Protein_751 | restriction endonuclease subunit S | - |
| LD199_RS04035 (LD199_04035) | 808704..809114 | + | 411 | WP_001808705.1 | IS21 family transposase | - |
| LD199_RS04040 (LD199_04040) | 809099..809260 | + | 162 | Protein_753 | transposase | - |
| LD199_RS04045 (LD199_04045) | 809238..809339 | - | 102 | WP_001792025.1 | hypothetical protein | - |
| - | 809377..809434 | + | 58 | - | - | Antitoxin |
| LD199_RS04050 (LD199_04050) | 809462..809557 | - | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
| LD199_RS04055 (LD199_04055) | 809702..810714 | + | 1013 | Protein_756 | IS3 family transposase | - |
| LD199_RS04060 (LD199_04060) | 810912..811484 | - | 573 | WP_000414216.1 | hypothetical protein | - |
| LD199_RS04065 (LD199_04065) | 811585..811926 | - | 342 | WP_000627540.1 | DUF3969 family protein | - |
| LD199_RS04070 (LD199_04070) | 811967..812593 | - | 627 | WP_061823501.1 | hypothetical protein | - |
| LD199_RS04075 (LD199_04075) | 812668..813663 | - | 996 | WP_000070642.1 | DUF4352 domain-containing protein | - |
| LD199_RS04080 (LD199_04080) | 813744..814394 | - | 651 | WP_001795210.1 | excalibur calcium-binding domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | selk / hlgA / lukD | 782547..815152 | 32605 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T219767 WP_001801861.1 NZ_CP084878:c809557-809462 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
>T219767 NZ_CP116692:c1758353-1758084 [Agrobacterium tumefaciens]
ATGAAGCTGGTCTGGACGCTGAGTTCATGGGACGACTATGAGTTCTGGCAAAGAACCGATGCTCGCATGGTCGAGAAAAT
AAACGATCTTATCCGAAATGCCAAACGCACGCCCTTTGCAGGGCTTGGGAAACCGGAGCCTCTGAAGGGCGATATGGCAG
GATATTGGTCTCGGCGGATTACCGCCGAGCATCGGTTTGTCTACCGTGTATCCGGGTCCGGAAGCGAGCAACGGCTGGAA
ATCATTCAGTGCCGCTTCCATTACCAATAA
ATGAAGCTGGTCTGGACGCTGAGTTCATGGGACGACTATGAGTTCTGGCAAAGAACCGATGCTCGCATGGTCGAGAAAAT
AAACGATCTTATCCGAAATGCCAAACGCACGCCCTTTGCAGGGCTTGGGAAACCGGAGCCTCTGAAGGGCGATATGGCAG
GATATTGGTCTCGGCGGATTACCGCCGAGCATCGGTTTGTCTACCGTGTATCCGGGTCCGGAAGCGAGCAACGGCTGGAA
ATCATTCAGTGCCGCTTCCATTACCAATAA
Antitoxin
Download Length: 58 bp
>AT219767 NZ_CP084878:809377-809434 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
