Detailed information of TA system TA219142

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 2414801..2415021
• Replicon: chromosome
• Accession: NZ_CP084683
• Organism: Escherichia coli strain BL21(RP)

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: J7R083
• Locus tag: LGS58_RS11730
• Protein ID: WP_000170963.1
• Coordinates: 2414801..2414908 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	2414955..2415021 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGS58_RS11705	2410647..2411729	+	1083	WP_000804726.1	peptide chain release factor 1	-
LGS58_RS11710	2411729..2412562	+	834	WP_000456454.1	peptide chain release factor N(5)-glutamine methyltransferase	-
LGS58_RS11715	2412559..2412951	+	393	WP_000200373.1	invasion regulator SirB2	-
LGS58_RS11720	2412955..2413764	+	810	WP_001257044.1	invasion regulator SirB1	-
LGS58_RS11725	2413800..2414654	+	855	WP_000811065.1	3-deoxy-8-phosphooctulonate synthase	-
LGS58_RS11730	2414801..2414908	-	108	WP_000170963.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	2414955..2415021	+	67	-	-	Antitoxin
LGS58_RS11735	2415391..2416848	-	1458	WP_000156701.1	NADH-quinone oxidoreductase subunit NuoN	-
LGS58_RS11740	2416855..2418384	-	1530	WP_000926441.1	NADH-quinone oxidoreductase subunit M	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3971.74 Da
• Isoelectric Point: 11.4779

>T219142 WP_000170963.1 NZ_CP084683:c2414908-2414801 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK

Nucleotide

• Length: 108 bp

>T219142 NZ_CP116191:304280-304453 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTCTTCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Nucleotide

• Length: 67 bp

>AT219142 NZ_CP084683:2414955-2415021 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Structures

Antitoxin