219129

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4325402..4326098 Replicon chromosome
Accession NZ_CP084664
Organism UNVERIFIED_ORG: Hafnia paralvei strain FDAARGOS_1502

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag LA328_RS19925 Protein ID WP_175320678.1
Coordinates 4325787..4326098 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LA328_RS19920 Protein ID WP_175320679.1
Coordinates 4325402..4325800 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA328_RS19905 (LA328_19905) 4322144..4322986 + 843 WP_175320680.1 helix-turn-helix domain-containing protein -
LA328_RS19910 (LA328_19910) 4323303..4323590 + 288 WP_008815650.1 PapB/FocB family fimbrial expression transcriptional regulator -
LA328_RS19915 (LA328_19915) 4323672..4325159 - 1488 WP_004096959.1 glycerol-3-phosphate dehydrogenase -
LA328_RS19920 (LA328_19920) 4325402..4325800 - 399 WP_175320679.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LA328_RS19925 (LA328_19925) 4325787..4326098 - 312 WP_175320678.1 type II toxin-antitoxin system MqsR family toxin Toxin
LA328_RS19930 (LA328_19930) 4326348..4327106 - 759 WP_004096965.1 DeoR/GlpR family transcriptional regulator -
LA328_RS19935 (LA328_19935) 4327140..4327976 - 837 WP_039186087.1 rhomboid family intramembrane serine protease GlpG -
LA328_RS19940 (LA328_19940) 4328129..4328458 - 330 WP_039186089.1 thiosulfate sulfurtransferase GlpE -
LA328_RS19945 (LA328_19945) 4328732..4329166 + 435 WP_039186093.1 hypothetical protein -
LA328_RS19950 (LA328_19950) 4329964..4330707 - 744 WP_008815656.1 glycerophosphodiester phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12056.92 Da        Isoelectric Point: 7.4315

>T219129 WP_175320678.1 NZ_CP084664:c4326098-4325787 [Hafnia paralvei]
MEKRTPHCRLEKIRSLIGKGLIRATKSAHRNAELINFSLADMYRVVSELSPHDFYKSMTAYDDHRIWQDVYYCHLDTISL
YLKLTVIDDVLIVSFKELDHAVS

Download         Length: 312 bp

>T219129 NZ_CP116188:c2678267-2678164 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14648.87 Da        Isoelectric Point: 6.4578

>AT219129 WP_175320679.1 NZ_CP084664:c4325800-4325402 [Hafnia paralvei]
MQCPECGSKNTVKEYRDIPFTYKGQSTVVKAVGADWCLNCGEGVIFKEESLRIDGILSEFNKQVNASIIEPEFVIAMRKK
LNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKHPELLAEIRD

Download         Length: 399 bp

>AT219129 NZ_CP116188:2678126-2678397 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References