Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 4014669..4015211 Replicon chromosome
Accession NZ_CP084656
Organism Pectobacterium versatile strain SR1

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag LGL96_RS17815 Protein ID WP_103972206.1
Coordinates 4014933..4015211 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag LGL96_RS17810 Protein ID WP_103972205.1
Coordinates 4014669..4014929 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL96_RS17785 (LGL96_17785) 4010123..4011037 + 915 WP_111779056.1 glycosyltransferase family 2 protein -
LGL96_RS17790 (LGL96_17790) 4011053..4012204 + 1152 WP_111779064.1 UDP-galactopyranose mutase -
LGL96_RS17795 (LGL96_17795) 4012238..4013083 - 846 WP_165708476.1 dTDP-4-dehydrorhamnose reductase -
LGL96_RS17800 (LGL96_17800) 4013080..4013616 - 537 WP_102116589.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
LGL96_RS17805 (LGL96_17805) 4013618..4014487 - 870 WP_040031349.1 glucose-1-phosphate thymidylyltransferase RfbA -
LGL96_RS17810 (LGL96_17810) 4014669..4014929 + 261 WP_103972205.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LGL96_RS17815 (LGL96_17815) 4014933..4015211 + 279 WP_103972206.1 type II toxin-antitoxin system YafQ family toxin Toxin
LGL96_RS17820 (LGL96_17820) 4015444..4016340 + 897 WP_103860289.1 sugar phosphate nucleotidyltransferase -
LGL96_RS17825 (LGL96_17825) 4016571..4017977 + 1407 WP_039492568.1 NADP-dependent phosphogluconate dehydrogenase -
LGL96_RS17830 (LGL96_17830) 4018444..4018737 + 294 WP_010296810.1 hypothetical protein -
LGL96_RS17835 (LGL96_17835) 4018813..4019490 + 678 WP_162847994.1 YjbF family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - wza / wbtL 3988903..4015211 26308


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11156.81 Da        Isoelectric Point: 10.0684

>T219115 WP_103972206.1 NZ_CP084656:4014933-4015211 [Pectobacterium versatile]
MKKQREIAYSGQFQRDVKKAQRRHKNMNKLKTLMQLLLEDKRPLPQEYQDHPLQGNYKGYRDAHIEPDWLLIYKLTDDVL
RFERTGTHADLF

Download         Length: 279 bp

>T219115 NZ_CP116182:99261-99641 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAACCGCTACGGCGGCCTGCCGGGAATGTC
TGATCCGGGCAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGTTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACCGTAGGGGCTGCGACCGG
AGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9282.72 Da        Isoelectric Point: 5.6706

>AT219115 WP_103972205.1 NZ_CP084656:4014669-4014929 [Pectobacterium versatile]
MAANAFVRARIDENLKNEAAEVLASMGLTVSDLVRITLTKVAKEKALPFDMHVPNKLTAQTMADSEKGVDVHTAKDAADL
FDKLGI

Download         Length: 261 bp

>AT219115 NZ_CP116182:99040-99261 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAGGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References