219096

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2229537..2230888 Replicon chromosome
Accession NZ_CP084656
Organism Pectobacterium versatile strain SR1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag LGL96_RS09815 Protein ID WP_205539717.1
Coordinates 2229848..2230888 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag LGL96_RS09810 Protein ID WP_040032232.1
Coordinates 2229537..2229851 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL96_RS09785 (LGL96_09785) 2225362..2226396 + 1035 WP_103862830.1 putative FMN-dependent luciferase-like monooxygenase -
LGL96_RS09790 (LGL96_09790) 2226393..2227526 + 1134 WP_103971661.1 alkylhydroperoxidase domain protein -
LGL96_RS09795 (LGL96_09795) 2227583..2228092 - 510 WP_039542420.1 phenolic acid decarboxylase -
LGL96_RS09800 (LGL96_09800) 2228195..2229067 + 873 WP_103862832.1 LysR family transcriptional regulator -
LGL96_RS09805 (LGL96_09805) 2229226..2229552 + 327 WP_103862833.1 helix-turn-helix domain-containing protein -
LGL96_RS09810 (LGL96_09810) 2229537..2229851 + 315 WP_040032232.1 HipA N-terminal domain-containing protein Antitoxin
LGL96_RS09815 (LGL96_09815) 2229848..2230888 + 1041 WP_205539717.1 HipA domain-containing protein Toxin
LGL96_RS09820 (LGL96_09820) 2230949..2231572 - 624 WP_225586316.1 LysE family translocator -
LGL96_RS09825 (LGL96_09825) 2231851..2232606 + 756 WP_225586317.1 thiol:disulfide interchange protein DsbG -
LGL96_RS09830 (LGL96_09830) 2232641..2233546 - 906 WP_225586318.1 siderophore-interacting protein -
LGL96_RS09835 (LGL96_09835) 2233804..2234055 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
LGL96_RS09840 (LGL96_09840) 2234052..2234339 + 288 WP_225586319.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2226436..2270671 44235


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39511.47 Da        Isoelectric Point: 6.3391

>T219096 WP_205539717.1 NZ_CP084656:2229848-2230888 [Pectobacterium versatile]
MTTCRILLTPLTHEEEMATGYSRKGLKHLAGSIHASPDLRFTRQQFMHDLPQTQKGMSISGYQPKIQMVLQDRAFIVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEKADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIRADGRQYVSYERLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSHSGQLMLSPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETADGEYLGMDFILFGQRIGLSEKLTKKLLADFIKEAECVESTYRDSFMP
AEAIDTTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T219096 NZ_CP116181:c604139-603675 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGATGCTTTAGTTGC
CGAAGTCGAGGCATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGTAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11924.66 Da        Isoelectric Point: 6.4642

>AT219096 WP_040032232.1 NZ_CP084656:2229537-2229851 [Pectobacterium versatile]
VRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPLQTEIFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDEA

Download         Length: 315 bp

>AT219096 NZ_CP116181:c604474-604139 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTAACGCTGTACTGACCACTGAATCAAAGGTCACTATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCTGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAT
CCGCAAAAAACTCGTCCATTCGACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGACGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References