Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 3377132..3377674 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag LGL95_RS15050 Protein ID WP_226305804.1
Coordinates 3377132..3377332 (-) Length 67 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag LGL95_RS15055 Protein ID WP_102116587.1
Coordinates 3377414..3377674 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS15030 (LGL95_15030) 3372858..3373535 - 678 WP_164500087.1 YjbF family lipoprotein -
LGL95_RS15035 (LGL95_15035) 3373611..3373901 - 291 WP_127030966.1 hypothetical protein -
LGL95_RS15040 (LGL95_15040) 3374367..3375773 - 1407 WP_039492568.1 NADP-dependent phosphogluconate dehydrogenase -
LGL95_RS15045 (LGL95_15045) 3376004..3376900 - 897 WP_127030964.1 sugar phosphate nucleotidyltransferase -
LGL95_RS15050 (LGL95_15050) 3377132..3377332 - 201 WP_226305804.1 type II toxin-antitoxin system YafQ family toxin Toxin
LGL95_RS15055 (LGL95_15055) 3377414..3377674 - 261 WP_102116587.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LGL95_RS15060 (LGL95_15060) 3377861..3378730 + 870 WP_127030963.1 glucose-1-phosphate thymidylyltransferase RfbA -
LGL95_RS15065 (LGL95_15065) 3378732..3379268 + 537 WP_226305805.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
LGL95_RS15070 (LGL95_15070) 3379265..3380110 + 846 WP_226305806.1 dTDP-4-dehydrorhamnose reductase -
LGL95_RS15075 (LGL95_15075) 3380200..3381143 - 944 Protein_2951 IS630 family transposase -
LGL95_RS15080 (LGL95_15080) 3381476..3382300 - 825 WP_226305807.1 glycosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - wbtL / wzb / wza 3377132..3401117 23985
- flank IS/Tn - - 3380524..3380766 242


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-65)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 67 a.a.        Molecular weight: 7942.15 Da        Isoelectric Point: 7.3145

>T219059 WP_226305804.1 NZ_CP084654:c3377332-3377132 [Pectobacterium versatile]
MNKLKTLMQLFLEDKRPLPQEYQDHPLQGNYKGYRDAHIKPDWLLIYKLTDDVLRFERTGTHADLL

Download         Length: 201 bp

>T219059 NZ_CP116169:2358621-2359943 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTTTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9308.75 Da        Isoelectric Point: 5.0628

>AT219059 WP_102116587.1 NZ_CP084654:c3377674-3377414 [Pectobacterium versatile]
MAANAFVRARIDENLKNEAAEVLASMGLTVSDLVRITLTKVAKEKALPFDMHVPNKLTAQTMADSEKGVDVYTAKDAADL
FDKLGI

Download         Length: 261 bp

>AT219059 NZ_CP116169:2358355-2358621 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTAGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References