Detailed information of TA system TA218345

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2057073..2057221
• Replicon: chromosome
• Accession: NZ_CP084235
• Organism: Staphylococcus haemolyticus strain SE2.14

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: RES5_RS10140
• Protein ID: WP_103421963.1
• Coordinates: 2057073..2057168 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2057186..2057221 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RES5_RS10110 (RES5_010110)	2053277..2053693	-	417	WP_011276552.1	DUF1934 family protein	-
RES5_RS10115 (RES5_010115)	2053984..2054079	+	96	WP_107109960.1	type I toxin-antitoxin system Fst family toxin	-
RES5_RS10120 (RES5_010120)	2054509..2054601	-	93	Protein_1968	IS6 family transposase	-
RES5_RS10125 (RES5_010125)	2055051..2055569	-	519	WP_161511582.1	type 1 glutamine amidotransferase domain-containing protein	-
RES5_RS10130 (RES5_010130)	2055657..2056292	-	636	WP_161511581.1	3-hexulose-6-phosphate synthase	-
RES5_RS10135 (RES5_010135)	2056395..2056745	+	351	WP_161511580.1	helix-turn-helix domain-containing protein	-
RES5_RS10140 (RES5_010140)	2057073..2057168	+	96	WP_103421963.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2057186..2057221	+	36	-	-	Antitoxin
RES5_RS10145 (RES5_010145)	2057294..2059915	-	2622	WP_161511579.1	AAA family ATPase	-
RES5_RS10150 (RES5_010150)	2060128..2060898	-	771	WP_213987897.1	ABC transporter permease	-
RES5_RS10155 (RES5_010155)	2060900..2061595	-	696	WP_161517093.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-126)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3671.42 Da
• Isoelectric Point: 9.5124

>T218345 WP_103421963.1 NZ_CP084235:2057073-2057168 [Staphylococcus haemolyticus]
MLEIFVHITTTVISGCIIALFTHWLRNRKEK

Nucleotide

• Length: 96 bp

>T218345 NZ_CP115843:386002-386421 [Agrobacterium fabacearum]
ATGATCTTGCTTGACACCAACGTCATATCCGAACCTTGGAAACCGGTTCCGGACGAGGCGGTGATTGCCTGGTTGGACGC
CCAAGCTGTCGAAACGCTGTTCATCTCCGCAATAACGATTGCGGAACTTCGCTTCGGAATTGCTGCTATGCCTTCAGGCA
GACGGCAAACTATCCTCCGCGACCGTCTCGAGGGCGAGGTGCTGCCACACTTTTCCGGCCGCATCCTGTCCTTCGATCTG
ACTACTTCTCAGTTCTACTCTGAACTGATGGCACGCGCTCGAGCGTCTGGGAAAGCGATCGGCACGGCCGATGGCTACAT
TGCAGCCACAGCGGCAGCAAATGGCCTCACGATCTCAACTCGCGATACAAGCCCTTTCGAGGCTGCCGGGGTGAAAGTGA
TCAATCCCTGGTCCAGATAA

Antitoxin

Nucleotide

• Length: 36 bp

>AT218345 NZ_CP084235:2057186-2057221 [Staphylococcus haemolyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin