Detailed information of TA system TA218338

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2057137..2057285
• Replicon: chromosome
• Accession: NZ_CP084229
• Organism: Staphylococcus haemolyticus strain SE3.8

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: RES6_RS10130
• Protein ID: WP_103421963.1
• Coordinates: 2057137..2057232 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2057250..2057285 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RES6_RS10100 (RES6_010100)	2053341..2053757	-	417	WP_011276552.1	DUF1934 family protein	-
RES6_RS10105 (RES6_010105)	2054048..2054143	+	96	WP_107109960.1	type I toxin-antitoxin system Fst family toxin	-
RES6_RS10110 (RES6_010110)	2054573..2054665	-	93	Protein_1961	IS6 family transposase	-
RES6_RS10115 (RES6_010115)	2055115..2055633	-	519	WP_161511582.1	type 1 glutamine amidotransferase domain-containing protein	-
RES6_RS10120 (RES6_010120)	2055721..2056356	-	636	WP_161511581.1	3-hexulose-6-phosphate synthase	-
RES6_RS10125 (RES6_010125)	2056459..2056809	+	351	WP_161511580.1	helix-turn-helix domain-containing protein	-
RES6_RS10130 (RES6_010130)	2057137..2057232	+	96	WP_103421963.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2057250..2057285	+	36	-	-	Antitoxin
RES6_RS10135 (RES6_010135)	2057358..2059979	-	2622	WP_161511579.1	AAA family ATPase	-
RES6_RS10140 (RES6_010140)	2060192..2060962	-	771	WP_213987897.1	ABC transporter permease	-
RES6_RS10145 (RES6_010145)	2060964..2061659	-	696	WP_161517093.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3671.42 Da
• Isoelectric Point: 9.5124

>T218338 WP_103421963.1 NZ_CP084229:2057137-2057232 [Staphylococcus haemolyticus]
MLEIFVHITTTVISGCIIALFTHWLRNRKEK

Nucleotide

• Length: 96 bp

>T218338 NZ_CP115837:c4698877-4698593 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCTGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin

Nucleotide

• Length: 36 bp

>AT218338 NZ_CP084229:2057250-2057285 [Staphylococcus haemolyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin