Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2158924..2159429 Replicon chromosome
Accession NZ_CP084222
Organism Arsenophonus apicola strain ArsBeeUS

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LDL57_RS10295 Protein ID WP_180560959.1
Coordinates 2159172..2159429 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LDL57_RS10290 Protein ID WP_180560958.1
Coordinates 2158924..2159175 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDL57_RS10260 (LDL57_10260) 2154569..2155329 + 761 Protein_1998 IS21-like element helper ATPase IstB -
LDL57_RS10265 (LDL57_10265) 2155370..2156122 + 753 WP_225505555.1 S-type pyocin domain-containing protein -
LDL57_RS10270 (LDL57_10270) 2156426..2157383 + 958 Protein_2000 colicin E3/pyocin S6 family cytotoxin -
LDL57_RS10275 (LDL57_10275) 2157380..2157652 + 273 WP_180560955.1 colicin immunity domain-containing protein -
LDL57_RS10280 (LDL57_10280) 2157883..2158107 + 225 WP_180560956.1 hypothetical protein -
LDL57_RS10285 (LDL57_10285) 2158110..2158367 + 258 WP_180560957.1 bacteriocin immunity protein -
LDL57_RS10290 (LDL57_10290) 2158924..2159175 + 252 WP_180560958.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
LDL57_RS10295 (LDL57_10295) 2159172..2159429 + 258 WP_180560959.1 Txe/YoeB family addiction module toxin Toxin
LDL57_RS10300 (LDL57_10300) 2159687..2160979 - 1293 WP_180560960.1 serine--tRNA ligase -
LDL57_RS10305 (LDL57_10305) 2161089..2162432 - 1344 WP_180560961.1 replication-associated recombination protein A -
LDL57_RS10310 (LDL57_10310) 2162434..2163051 - 618 WP_180561012.1 outer membrane lipoprotein chaperone LolA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10457.11 Da        Isoelectric Point: 9.9171

>T218328 WP_180560959.1 NZ_CP084222:2159172-2159429 [Arsenophonus apicola]
MKLIFTEQSWNDYLYWQQIDKKVIKRINELIKDIKRELFSGIGKPEPLKHNLTGFWSRRITEEHRLIYRLTDKSLEIASC
RYHYN

Download         Length: 258 bp

>T218328 NZ_CP115837:349084-349431 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTCCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCGATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9439.66 Da        Isoelectric Point: 4.5836

>AT218328 WP_180560958.1 NZ_CP084222:2158924-2159175 [Arsenophonus apicola]
MKTVNYTDARQNLTSIMNEAIDDRIPILITRQKGIPCVLLSHDEYQSLEETAYLLRSPANARHLLDSIDELNAGKGIERD
IQE

Download         Length: 252 bp

>AT218328 NZ_CP115837:349431-349730 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGAAAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGACTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References