Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 183529..183751 Replicon chromosome
Accession NZ_CP084209
Organism Escherichia coli strain EC2648-R2

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag LDB16_RS00880 Protein ID WP_000141634.1
Coordinates 183644..183751 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 183529..183595 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDB16_RS00860 178970..179872 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
LDB16_RS00865 179883..180866 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
LDB16_RS00870 180863..181867 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
LDB16_RS00875 181897..183168 - 1272 WP_001295225.1 aromatic amino acid transport family protein -
- 183529..183595 - 67 - - Antitoxin
LDB16_RS00880 183644..183751 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
LDB16_RS00885 183838..185517 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
LDB16_RS00890 185514..185705 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
LDB16_RS00895 185702..187273 - 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
LDB16_RS00900 187546..187734 + 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
LDB16_RS00905 187770..188498 + 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T218267 WP_000141634.1 NZ_CP084209:183644-183751 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T218267 NZ_CP115714:1878219-1878321 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 67 bp

>AT218267 NZ_CP084209:c183595-183529 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References