218189

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 69568..70219 Replicon plasmid pCB1A
Accession NZ_CP084198
Organism Pantoea agglomerans strain CB1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LDO72_RS19700 Protein ID WP_069026837.1
Coordinates 69568..69912 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LDO72_RS19705 Protein ID WP_069026836.1
Coordinates 69905..70219 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO72_RS19680 (LDO72_19700) 65900..66370 + 471 WP_275103237.1 GNAT family N-acetyltransferase -
LDO72_RS19685 (LDO72_19705) 66474..67352 + 879 WP_033768811.1 23S rRNA pseudouridine(2604) synthase RluF -
LDO72_RS19690 (LDO72_19710) 67411..68469 - 1059 WP_275103238.1 SDR family oxidoreductase -
LDO72_RS19695 (LDO72_19715) 68567..69478 + 912 WP_275103239.1 LysR family transcriptional regulator -
LDO72_RS19700 (LDO72_19720) 69568..69912 + 345 WP_069026837.1 toxin Toxin
LDO72_RS19705 (LDO72_19725) 69905..70219 + 315 WP_069026836.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LDO72_RS19710 (LDO72_19730) 70429..71100 + 672 WP_115388259.1 hypothetical protein -
LDO72_RS19715 (LDO72_19735) 71191..72042 - 852 WP_275103240.1 Vmh family MBL fold metallo-hydrolase -
LDO72_RS19720 (LDO72_19740) 72188..73069 + 882 WP_031594128.1 LysR family transcriptional regulator -
LDO72_RS19725 (LDO72_19745) 73108..73527 + 420 WP_031594127.1 VOC family protein -
LDO72_RS19730 (LDO72_19750) 74016..74318 + 303 WP_069026834.1 type 1 fimbrial protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..569555 569555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(18-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13486.26 Da        Isoelectric Point: 9.6381

>T218189 WP_069026837.1 NZ_CP084198:69568-69912 [Pantoea agglomerans]
MDALFIELSSFQKYRADYLNDDQYRLFQNMLLADPEKGDVIPDTGGLRKVRFRDERRHKGARGGIRVIYYWTNTQGQFIL
FTIYDKDQRDDLTRQQRDALATALNVIKKGLRHD

Download         Length: 345 bp

>T218189 NZ_CP115672:c2308326-2307841 [Enterobacter hormaechei]
GTGGGACGTGTAACAGCACCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGTGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTGAAAAACCAGGCGCTCGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGGAGCGTTAACCATACGCAAGCGACAGGTAATCTGCGGCGTAACATG
CCGGATCCCATACCCGTGATTATACTTGCCCGTCTGGCTGTGGATGTCTCGTTACGCGGAAACGGGTTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATCGGGGTGCGAGCGATCATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTCAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCCGGCTTCCT
CAGTAG

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12022.84 Da        Isoelectric Point: 9.8806

>AT218189 WP_069026836.1 NZ_CP084198:69905-70219 [Pantoea agglomerans]
MTERDIFSELMTGMQELKDHQEGKITLKSYKVTKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRARP
NAQAVLLIRMVQQNPETLKTLAKL

Download         Length: 315 bp

>AT218189 NZ_CP115672:c2308580-2308314 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTCAATCTCAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGCACGGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAGAATGTGATCCTCGATCGGCGTGTATTCAATT
TTAACGATGAACAGTACGCAGAGTTCATTGACATGCTCGATGCCCCGGTCGCGGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References