Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/RelE-HTH |
Location | 2907173..2907777 | Replicon | chromosome |
Accession | NZ_CP084197 | ||
Organism | Pantoea agglomerans strain CB1 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | LDO72_RS13720 | Protein ID | WP_010669712.1 |
Coordinates | 2907173..2907484 (+) | Length | 104 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | LDO72_RS13725 | Protein ID | WP_010669711.1 |
Coordinates | 2907484..2907777 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LDO72_RS13700 (LDO72_13700) | 2902183..2903130 | - | 948 | WP_010669715.1 | ABC transporter ATP-binding protein | - |
LDO72_RS13705 (LDO72_13705) | 2903123..2904298 | - | 1176 | WP_275102433.1 | ABC transporter permease | - |
LDO72_RS13710 (LDO72_13710) | 2904302..2905213 | - | 912 | WP_275102434.1 | ABC transporter substrate-binding protein | - |
LDO72_RS13715 (LDO72_13715) | 2905520..2906995 | + | 1476 | WP_275102435.1 | MFS transporter | - |
LDO72_RS13720 (LDO72_13720) | 2907173..2907484 | + | 312 | WP_010669712.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LDO72_RS13725 (LDO72_13725) | 2907484..2907777 | + | 294 | WP_010669711.1 | NadS family protein | Antitoxin |
LDO72_RS13730 (LDO72_13730) | 2907914..2908456 | - | 543 | WP_275102436.1 | isopentenyl-diphosphate Delta-isomerase | - |
LDO72_RS13735 (LDO72_13735) | 2908603..2910498 | - | 1896 | WP_033779530.1 | methyl-accepting chemotaxis protein | - |
LDO72_RS13740 (LDO72_13740) | 2910690..2911799 | - | 1110 | WP_022625997.1 | suppressor of fused domain protein | - |
LDO72_RS13745 (LDO72_13745) | 2912129..2912356 | - | 228 | WP_275102437.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 a.a. Molecular weight: 11997.67 Da Isoelectric Point: 5.8988
>T218185 WP_010669712.1 NZ_CP084197:2907173-2907484 [Pantoea agglomerans]
MLFIETPVFTEDVKELLSDDEYREFQQFMADNPGWGDVIQNTGGLRKVRWAAKGKGKRGGVRVIYYYKVSESQIRLLLIY
KKGVQDDLSEDEKHLLRALNEGW
MLFIETPVFTEDVKELLSDDEYREFQQFMADNPGWGDVIQNTGGLRKVRWAAKGKGKRGGVRVIYYYKVSESQIRLLLIY
KKGVQDDLSEDEKHLLRALNEGW
Download Length: 312 bp
>T218185 NZ_CP115671:2842897-2843217 [Brevundimonas vesicularis]
ATGCTCCGCCTAAGCCGCGCGGCGCGGGCGGACTTGCAGCAGGTCTATCTGCAAGGCCTCGAGCTGTTCGGGAGCCGTCA
GGCCGATGACTATATCGAGGGTCTGTTCGCGAAACTGGACTTGCTTGCCGATTTTCCACGTCTTGGGGCGGCTCGACCGG
AGTTGAGCGCGGACGCCCATGTGATCTTCTACAAAAGCCACGCCATTCTCTATCGAATCGACGATGCGGACATGTTCGTT
CGACGCATTCGGCACGCGCTTGAGGACTGGCAGTCCGACGCGCCAGGCGTCGGATCGAGCGACGAACGGAGCGAACCATG
A
ATGCTCCGCCTAAGCCGCGCGGCGCGGGCGGACTTGCAGCAGGTCTATCTGCAAGGCCTCGAGCTGTTCGGGAGCCGTCA
GGCCGATGACTATATCGAGGGTCTGTTCGCGAAACTGGACTTGCTTGCCGATTTTCCACGTCTTGGGGCGGCTCGACCGG
AGTTGAGCGCGGACGCCCATGTGATCTTCTACAAAAGCCACGCCATTCTCTATCGAATCGACGATGCGGACATGTTCGTT
CGACGCATTCGGCACGCGCTTGAGGACTGGCAGTCCGACGCGCCAGGCGTCGGATCGAGCGACGAACGGAGCGAACCATG
A
Antitoxin
Download Length: 98 a.a. Molecular weight: 10741.39 Da Isoelectric Point: 10.6798
>AT218185 WP_010669711.1 NZ_CP084197:2907484-2907777 [Pantoea agglomerans]
MDKKLFERLKESMTQMNEIVEGSRAPARESTVTAVKVKAIRNATGLSQSGFAKLISVNVDTLKNWEQGRREPTGPAKALL
RAIERDPQHVIPALADK
MDKKLFERLKESMTQMNEIVEGSRAPARESTVTAVKVKAIRNATGLSQSGFAKLISVNVDTLKNWEQGRREPTGPAKALL
RAIERDPQHVIPALADK
Download Length: 294 bp
>AT218185 NZ_CP115671:2842652-2842897 [Brevundimonas vesicularis]
ATGGCGACGATGAACATCTCCCTGCCCGATCCGATGAAGGCCTGGGTCGAGGAACAGGCGAAATCCGGGCGCTACGCCAA
TACGTCGGACGTGGTGCGCGACCTGATCCGCCGCGAGCAGGTCAAGGCCGAGAAGATCGCGCATTGGCAAAGGCTGATCG
TCGAGGCCGACGCCTCCGGTGTTTCCGACCAGTCGCCACGTGAAGTGATCGAGGAACTGCGCGCCCAGTTGCGTCGCGCC
TCTTGA
ATGGCGACGATGAACATCTCCCTGCCCGATCCGATGAAGGCCTGGGTCGAGGAACAGGCGAAATCCGGGCGCTACGCCAA
TACGTCGGACGTGGTGCGCGACCTGATCCGCCGCGAGCAGGTCAAGGCCGAGAAGATCGCGCATTGGCAAAGGCTGATCG
TCGAGGCCGACGCCTCCGGTGTTTCCGACCAGTCGCCACGTGAAGTGATCGAGGAACTGCGCGCCCAGTTGCGTCGCGCC
TCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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