Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2907173..2907777 Replicon chromosome
Accession NZ_CP084197
Organism Pantoea agglomerans strain CB1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LDO72_RS13720 Protein ID WP_010669712.1
Coordinates 2907173..2907484 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LDO72_RS13725 Protein ID WP_010669711.1
Coordinates 2907484..2907777 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO72_RS13700 (LDO72_13700) 2902183..2903130 - 948 WP_010669715.1 ABC transporter ATP-binding protein -
LDO72_RS13705 (LDO72_13705) 2903123..2904298 - 1176 WP_275102433.1 ABC transporter permease -
LDO72_RS13710 (LDO72_13710) 2904302..2905213 - 912 WP_275102434.1 ABC transporter substrate-binding protein -
LDO72_RS13715 (LDO72_13715) 2905520..2906995 + 1476 WP_275102435.1 MFS transporter -
LDO72_RS13720 (LDO72_13720) 2907173..2907484 + 312 WP_010669712.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDO72_RS13725 (LDO72_13725) 2907484..2907777 + 294 WP_010669711.1 NadS family protein Antitoxin
LDO72_RS13730 (LDO72_13730) 2907914..2908456 - 543 WP_275102436.1 isopentenyl-diphosphate Delta-isomerase -
LDO72_RS13735 (LDO72_13735) 2908603..2910498 - 1896 WP_033779530.1 methyl-accepting chemotaxis protein -
LDO72_RS13740 (LDO72_13740) 2910690..2911799 - 1110 WP_022625997.1 suppressor of fused domain protein -
LDO72_RS13745 (LDO72_13745) 2912129..2912356 - 228 WP_275102437.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11997.67 Da        Isoelectric Point: 5.8988

>T218185 WP_010669712.1 NZ_CP084197:2907173-2907484 [Pantoea agglomerans]
MLFIETPVFTEDVKELLSDDEYREFQQFMADNPGWGDVIQNTGGLRKVRWAAKGKGKRGGVRVIYYYKVSESQIRLLLIY
KKGVQDDLSEDEKHLLRALNEGW

Download         Length: 312 bp

>T218185 NZ_CP115671:2842897-2843217 [Brevundimonas vesicularis]
ATGCTCCGCCTAAGCCGCGCGGCGCGGGCGGACTTGCAGCAGGTCTATCTGCAAGGCCTCGAGCTGTTCGGGAGCCGTCA
GGCCGATGACTATATCGAGGGTCTGTTCGCGAAACTGGACTTGCTTGCCGATTTTCCACGTCTTGGGGCGGCTCGACCGG
AGTTGAGCGCGGACGCCCATGTGATCTTCTACAAAAGCCACGCCATTCTCTATCGAATCGACGATGCGGACATGTTCGTT
CGACGCATTCGGCACGCGCTTGAGGACTGGCAGTCCGACGCGCCAGGCGTCGGATCGAGCGACGAACGGAGCGAACCATG
A

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10741.39 Da        Isoelectric Point: 10.6798

>AT218185 WP_010669711.1 NZ_CP084197:2907484-2907777 [Pantoea agglomerans]
MDKKLFERLKESMTQMNEIVEGSRAPARESTVTAVKVKAIRNATGLSQSGFAKLISVNVDTLKNWEQGRREPTGPAKALL
RAIERDPQHVIPALADK

Download         Length: 294 bp

>AT218185 NZ_CP115671:2842652-2842897 [Brevundimonas vesicularis]
ATGGCGACGATGAACATCTCCCTGCCCGATCCGATGAAGGCCTGGGTCGAGGAACAGGCGAAATCCGGGCGCTACGCCAA
TACGTCGGACGTGGTGCGCGACCTGATCCGCCGCGAGCAGGTCAAGGCCGAGAAGATCGCGCATTGGCAAAGGCTGATCG
TCGAGGCCGACGCCTCCGGTGTTTCCGACCAGTCGCCACGTGAAGTGATCGAGGAACTGCGCGCCCAGTTGCGTCGCGCC
TCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References