218181

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1563366..1564696 Replicon chromosome
Accession NZ_CP084197
Organism Pantoea agglomerans strain CB1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag LDO72_RS07360 Protein ID WP_275102951.1
Coordinates 1563366..1564388 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID A0A8X8DQB2
Locus tag LDO72_RS07365 Protein ID WP_033758331.1
Coordinates 1564385..1564696 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO72_RS07345 (LDO72_07350) 1559513..1560535 + 1023 WP_010247994.1 LLM class flavin-dependent oxidoreductase -
LDO72_RS07350 (LDO72_07355) 1560651..1560833 + 183 Protein_1424 hypothetical protein -
LDO72_RS07355 (LDO72_07360) 1561021..1563240 + 2220 WP_083068992.1 catalase/peroxidase HPI -
LDO72_RS07360 (LDO72_07365) 1563366..1564388 - 1023 WP_275102951.1 HipA domain-containing protein Toxin
LDO72_RS07365 (LDO72_07370) 1564385..1564696 - 312 WP_033758331.1 HipA N-terminal domain-containing protein Antitoxin
LDO72_RS07370 (LDO72_07375) 1564681..1565025 - 345 WP_275102952.1 XRE family transcriptional regulator -
LDO72_RS07380 (LDO72_07385) 1565802..1566923 + 1122 WP_033772166.1 Gfo/Idh/MocA family oxidoreductase -
LDO72_RS07385 (LDO72_07390) 1567023..1567853 - 831 WP_134160739.1 glycosyltransferase family 8 protein -
LDO72_RS07390 (LDO72_07395) 1567866..1569248 - 1383 WP_275102953.1 D-arabinono-1,4-lactone oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38595.16 Da        Isoelectric Point: 6.6647

>T218181 WP_275102951.1 NZ_CP084197:c1564388-1563366 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPDELAFVIKRYDRTASDNARLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENDAGNAPGMNSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTEI

Download         Length: 1023 bp

>T218181 NZ_CP115669:c4940593-4940282 [Pseudomonas sp. PSE14]
ATGAACTCTGAGCCTGCAAACGGACCCTCGCAGTACAAGCTTAGAATCAAGGACAGTGCAGAACGGGAATGGCGGAAACT
GCCTGAGCCAATCCGCGCCGCCTTCAAGAAGAAGCTGGCAGAGCGCCTTGCCAACCCACGGGTGGAGAAGGACAAACTCA
CCGGCATGAAGGACTGCTACAAGATCAAGCTGAAGGACGTCGGCTACCGGCTCGTCTATCGAGTGGATGATGGCGAGCTG
ATCATCGAGGTGATTGCTGCAGGAAAGCGGGAGCGCGGAGAGGCTTACGCTGCGGCGAGGAAACGGCTCTGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11669.46 Da        Isoelectric Point: 4.7953

>AT218181 WP_033758331.1 NZ_CP084197:c1564696-1564385 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGQSGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp

>AT218181 NZ_CP115669:c4940831-4940583 [Pseudomonas sp. PSE14]
ATGGCACATTCCGTTCTAGCGGATGTTGCAGCTTCTATCACTGAGCTGAAGAAGGACCCCATGGGGACCATCGAGGCCGG
GCGTGGCAAGACTGTGGTGATCTTGAATCGGAACGCTCCGGCGTTCTACGCAGTGCCTCCGGATGTCTATGAGCGGATGC
TGGAAGCTCTGGACGATGCCCACCTGGCCCGGCTCGTGAAGGAGCGCAGTGACGAACCTTCTCGGGAAATTTCATTGGAT
GAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References