Detailed information of TA system TA218126

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-SprA2AS/-
• Location: 2168571..2168769
• Replicon: chromosome
• Accession: NZ_CP084107
• Organism: Staphylococcus aureus strain CC49/ST49-MSSA

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: LB316_RS10700
• Protein ID: WP_078064523.1
• Coordinates: 2168665..2168769 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2168571..2168609 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LB316_RS10675	2164682..2165347	-	666	WP_001024086.1	SDR family oxidoreductase	-
LB316_RS10680	2165499..2165819	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
LB316_RS10685	2165821..2166801	+	981	WP_000019746.1	CDF family zinc efflux transporter CzrB	-
LB316_RS10690	2167067..2168158	+	1092	WP_000495687.1	hypothetical protein	-
LB316_RS10695	2168551..2168625	+	75	Protein_2069	hypothetical protein	-
-	2168571..2168609	+	39	-	-	Antitoxin
LB316_RS10700	2168665..2168769	-	105	WP_078064523.1	hypothetical protein	Toxin
LB316_RS10705	2168930..2169413	-	484	Protein_2071	recombinase family protein	-
LB316_RS10710	2169456..2170592	-	1137	WP_000115566.1	SAP domain-containing protein	-
LB316_RS10715	2170881..2170973	+	93	WP_031844941.1	hypothetical protein	-
LB316_RS10725	2171676..2172533	-	858	WP_029753951.1	HAD family hydrolase	-
LB316_RS10730	2172601..2173383	-	783	WP_000908184.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T218126 WP_078064523.1 NZ_CP084107:c2168769-2168665 [Staphylococcus aureus]
MLILERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T218126 NZ_CP115623:c3477950-3477561 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTCAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCGCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCCATTAA

Antitoxin

Nucleotide

• Length: 39 bp

>AT218126 NZ_CP084107:2168571-2168609 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin