218004

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4763782..4765133 Replicon chromosome
Accession NZ_CP084032
Organism Pectobacterium colocasium strain LJ1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag LCF41_RS21530 Protein ID WP_225086273.1
Coordinates 4764093..4765133 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag LCF41_RS21525 Protein ID WP_225086272.1
Coordinates 4763782..4764096 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCF41_RS21505 4759402..4761090 + 1689 WP_225086268.1 ABC transporter ATP-binding protein -
LCF41_RS21510 4761119..4762153 + 1035 WP_225086269.1 putative FMN-dependent luciferase-like monooxygenase -
LCF41_RS21515 4762150..4763283 + 1134 WP_225086270.1 alkylhydroperoxidase domain protein -
LCF41_RS21520 4763471..4763797 + 327 WP_225086271.1 helix-turn-helix domain-containing protein -
LCF41_RS21525 4763782..4764096 + 315 WP_225086272.1 HipA N-terminal domain-containing protein Antitoxin
LCF41_RS21530 4764093..4765133 + 1041 WP_225086273.1 HipA domain-containing protein Toxin
LCF41_RS21535 4765243..4765998 + 756 WP_225086274.1 thiol:disulfide interchange protein DsbG -
LCF41_RS21540 4766033..4766938 - 906 WP_225086275.1 siderophore-interacting protein -
LCF41_RS21545 4767211..4767462 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
LCF41_RS21550 4767459..4767746 + 288 WP_225086276.1 type II toxin-antitoxin system RelE/ParE family toxin -
LCF41_RS21555 4767848..4769200 - 1353 WP_225086277.1 glutathione-disulfide reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39563.45 Da        Isoelectric Point: 6.1061

>T218004 WP_225086273.1 NZ_CP084032:4764093-4765133 [Pectobacterium colocasium]
MTTCRILLTPLTHEEEIATGYSRKGLKHLAGSMHASPDLRFTRQQFMHDLPQIQKGMSISGYQPKIQMVLQDRTFTVVDH
QGMYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQTDDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIHTDGKQYISYEQLALFLSEHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGQLMLAPIYDFVSV
APYPSYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
AEAIDTTLRCYRHRLNLISILDAERI

Download         Length: 1041 bp

>T218004 NZ_CP115174:c4304454-4304200 [Sphingomonas sp. PAMB00755]
ATGACCGCCCTCAGCTTCTCCGACGCCCGCGCCAATCTGAAGGCGGTGATGGATCGTGCCGTGGCGGATCGCGCGCCGAT
CTCGATTACGCGCCAGAAGGCAGAGGGCGTGGTGATGATCTCGCAGAGCGAATGGGATTCGATTCAGGAGACGCTGTACT
TGCTGCGCTCTCCGAAGAATGCCGAGATGCTGCTGCGCGGGATCGCCGAACTCGACGCCGGCAAGGGCGAGGAGCATGAG
CTGATCGAGCCGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11804.49 Da        Isoelectric Point: 7.1961

>AT218004 WP_225086272.1 NZ_CP084032:4763782-4764096 [Pectobacterium colocasium]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKQSYIGPSLSLSLPIQTGAFRSTTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKA

Download         Length: 315 bp

>AT218004 NZ_CP115174:c4304203-4303937 [Sphingomonas sp. PAMB00755]
GTGAAGATCACATTCTCATCGGTCGCGTGGGATCACTATCTCTATTGGCAGGCCGAGGACGCCAAAGTGCTTGCCCGGCT
GAACGCGCTGCTCAAGGAATGTCAGCGCGATCCCTTCCGGGGCACCGGCAAGCCCGAGCCGCTCGGTGGCAATCTGTCGG
GCTGGTGGTCCCGCCGGATCAATTCAGAACATCGGCTGGTGTATCGGGTTGCCGGGAAGGGTGACAGGCAGGCGTTGGAA
GTGGCAGCTTGTCGGTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References