Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4459248..4460083 Replicon chromosome
Accession NZ_CP084032
Organism Pectobacterium colocasium strain LJ1

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag LCF41_RS20180 Protein ID WP_225086048.1
Coordinates 4459248..4459733 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag LCF41_RS20185 Protein ID WP_225086049.1
Coordinates 4459739..4460083 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCF41_RS20160 4454854..4456233 - 1380 WP_225086044.1 FtsX-like permease family protein -
LCF41_RS20165 4456230..4456922 - 693 WP_225086045.1 ABC transporter ATP-binding protein -
LCF41_RS20170 4456931..4457410 - 480 WP_225086046.1 hypothetical protein -
LCF41_RS20175 4457423..4459168 - 1746 WP_225086047.1 alkaline phosphatase -
LCF41_RS20180 4459248..4459733 - 486 WP_225086048.1 type II toxin-antitoxin system YhaV family toxin Toxin
LCF41_RS20185 4459739..4460083 - 345 WP_225086049.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
LCF41_RS20190 4460282..4463407 - 3126 WP_225086050.1 multidrug efflux RND transporter permease AcrD -
LCF41_RS20195 4463785..4464552 - 768 WP_225086051.1 pimeloyl-ACP methyl ester esterase BioH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 18770.60 Da        Isoelectric Point: 9.8930

>T218003 WP_225086048.1 NZ_CP084032:c4459733-4459248 [Pectobacterium colocasium]
MVDKRVINGWQLFTHPCFDVQFESLIVEVEQLRKKHPESYQKKQATKLLAAIVKVIRTEICGDPSQTKFRQGDTLGEGNK
HWFRAKFLGQYRLFFRYSEKHKTIILAWVNDSDTKRAYGDQHDAYKVFSGMLASGNPPGDWKQLLAESYKETMLTQMLVR
P

Download         Length: 486 bp

>T218003 NZ_CP115174:c4304203-4303937 [Sphingomonas sp. PAMB00755]
GTGAAGATCACATTCTCATCGGTCGCGTGGGATCACTATCTCTATTGGCAGGCCGAGGACGCCAAAGTGCTTGCCCGGCT
GAACGCGCTGCTCAAGGAATGTCAGCGCGATCCCTTCCGGGGCACCGGCAAGCCCGAGCCGCTCGGTGGCAATCTGTCGG
GCTGGTGGTCCCGCCGGATCAATTCAGAACATCGGCTGGTGTATCGGGTTGCCGGGAAGGGTGACAGGCAGGCGTTGGAA
GTGGCAGCTTGTCGGTATCATTATTGA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12802.40 Da        Isoelectric Point: 4.5491

>AT218003 WP_225086049.1 NZ_CP084032:c4460083-4459739 [Pectobacterium colocasium]
MFNLKSADVLLRADSRLTARSQTTIPSSVRDAMNLQPGEYIHYSVLPGGQVLISRREEAVDDDPVIHRFLHFLAEDMQHH
PENIKPFDQSLMSRASVLTAGMDIDLDAPLTDDE

Download         Length: 345 bp

>AT218003 NZ_CP115174:c4304454-4304200 [Sphingomonas sp. PAMB00755]
ATGACCGCCCTCAGCTTCTCCGACGCCCGCGCCAATCTGAAGGCGGTGATGGATCGTGCCGTGGCGGATCGCGCGCCGAT
CTCGATTACGCGCCAGAAGGCAGAGGGCGTGGTGATGATCTCGCAGAGCGAATGGGATTCGATTCAGGAGACGCTGTACT
TGCTGCGCTCTCCGAAGAATGCCGAGATGCTGCTGCGCGGGATCGCCGAACTCGACGCCGGCAAGGGCGAGGAGCATGAG
CTGATCGAGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References