Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 29569..30241 Replicon chromosome
Accession NZ_CP084032
Organism Pectobacterium colocasium strain LJ1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LCF41_RS00135 Protein ID WP_180779426.1
Coordinates 29855..30241 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LCF41_RS00130 Protein ID WP_180779427.1
Coordinates 29569..29868 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCF41_RS00110 24822..25811 + 990 WP_225086382.1 nucleoside hydrolase -
LCF41_RS00115 25811..26788 + 978 WP_225086383.1 ABC transporter permease -
LCF41_RS00120 26785..27693 + 909 WP_225086384.1 ABC transporter permease -
LCF41_RS00125 27733..29532 + 1800 WP_225086385.1 ABC transporter ATP-binding protein -
LCF41_RS00130 29569..29868 - 300 WP_180779427.1 XRE family transcriptional regulator Antitoxin
LCF41_RS00135 29855..30241 - 387 WP_180779426.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LCF41_RS00140 30457..30954 + 498 WP_225086386.1 GNAT family N-acetyltransferase -
LCF41_RS00145 31154..31411 - 258 WP_225086387.1 DUF1471 domain-containing protein -
LCF41_RS00150 31584..32384 - 801 WP_225086388.1 aliphatic sulfonates ABC transporter ATP-binding protein -
LCF41_RS00155 32381..33175 - 795 WP_225086389.1 aliphatic sulfonate ABC transporter permease SsuC -
LCF41_RS00160 33186..34328 - 1143 WP_225086390.1 FMNH2-dependent alkanesulfonate monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-113)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14834.84 Da        Isoelectric Point: 4.7331

>T217989 WP_180779426.1 NZ_CP084032:c30241-29855 [Pectobacterium colocasium]
MEVYRLAWEIVTRALFDTWFDEQTETVQEEVLAHLGILEEDGPQLGRPQVDQIKGSQYKNMKELRVQVGGHPFRTFFAFD
RTRKAIVLCAGDKKGENEKLFYERMIKIADAEFTSHLISPEVKEDGDI

Download         Length: 387 bp

>T217989 NZ_CP115150:3184591-3185076 [Enterobacter hormaechei subsp. xiangfangensis]
GTGGGACGTGTAACAGCACCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGCGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTGAAAAACCAGGCGCTCGGCGCAGCCCGAACCTTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGCAAGCGACAGGGAATCTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATTCTTGCCCGTCTGGCAGTTGATGTCTCGTTACGCGGAAACGGGTTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATCGGGGTGCGGGCGATTATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11082.10 Da        Isoelectric Point: 10.6442

>AT217989 WP_180779427.1 NZ_CP084032:c29868-29569 [Pectobacterium colocasium]
MATFKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVENDPKLSTLKRYVTALG
GKLTLDVTLPDGKRIALTL

Download         Length: 300 bp

>AT217989 NZ_CP115150:3184337-3184603 [Enterobacter hormaechei subsp. xiangfangensis]
ATGAAATCAGATGTTCAACTCAATCTCAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGCACGGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAGAATGTGATCCTCGATCGACGTGTATTCAATT
TTAACGATGAACAGTACGCAGAGTTCATTGACATGCTCGATGCCCCGGTCGCGGACGATCCGGCCATAGAAAAACTGCTG
GCAAGGAAACCACAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References