Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1495141..1495801 Replicon chromosome
Accession NZ_CP083809
Organism Pantoea agglomerans strain 33.1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LB453_RS09670 Protein ID WP_103796834.1
Coordinates 1495141..1495494 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LB453_RS09675 Protein ID WP_103796835.1
Coordinates 1495499..1495801 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LB453_RS09650 (LB453_09625) 1490842..1491615 + 774 WP_103796830.1 ABC transporter permease -
LB453_RS09655 (LB453_09630) 1491612..1492400 + 789 WP_103796831.1 ABC transporter ATP-binding protein -
LB453_RS09660 (LB453_09635) 1492397..1493608 + 1212 WP_224481706.1 M20 family metallopeptidase -
LB453_RS09665 (LB453_09640) 1493605..1494903 + 1299 WP_224481707.1 NtaA/DmoA family FMN-dependent monooxygenase -
LB453_RS09670 (LB453_09645) 1495141..1495494 + 354 WP_103796834.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LB453_RS09675 (LB453_09650) 1495499..1495801 + 303 WP_103796835.1 XRE family transcriptional regulator Antitoxin
LB453_RS09680 (LB453_09655) 1495902..1497278 - 1377 WP_103796836.1 MFS transporter -
LB453_RS09685 (LB453_09660) 1497313..1498692 - 1380 WP_103796837.1 MFS transporter -
LB453_RS09690 (LB453_09665) 1498739..1500775 - 2037 WP_103796838.1 alpha-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-89)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13418.52 Da        Isoelectric Point: 9.9394

>T217393 WP_103796834.1 NZ_CP083809:1495141-1495494 [Pantoea agglomerans]
VWAIKTTVRFDRWFTQLCDSDRASVLAAMIALQERGPGLPRPYADTLKGSRYINMKELRIQCRGHPIRAFFAFDPDRTGV
LLCAGHKAGNEKRFYAEMIPAADREFTGWLKGLREKE

Download         Length: 354 bp

>T217393 NZ_CP114201:c3313891-3313613 [Delftia acidovorans]
ATGATCCTCGATTTCAGATGTGCAGACACCCAGGCATTGATGCTTGGCAAGCGCGTTGCGCGGTTCGCCAACCTGGAGGC
CGCTGCCATGCGCAAGCTGGTGCAGCTGAACGCAGCGACCTCCCTGGAGTTCCTGCGCATTCCGCCAGGCAACAGACTGG
AGGCCCTTCAAGGAAGCCGCAGGGGCCAGTACAGCATTCGGATCAATGAGCAATGGCGCCTTTGCTTCGTCTGGGCAGAT
GGCCATGCCAGCCAGGTCGAGATCGTGGATTACCACTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11090.73 Da        Isoelectric Point: 5.6631

>AT217393 WP_103796835.1 NZ_CP083809:1495499-1495801 [Pantoea agglomerans]
MGRTLEQLIADEKPEVAAEAERSAAEILLNIHLAELREKVQKTQVEMAQTLGIRQPTVAGMEKPGRDLRLSTLKRYVEAA
GGKLHLDIELPDGTHYGFQV

Download         Length: 303 bp

>AT217393 NZ_CP114201:c3313600-3313298 [Delftia acidovorans]
ATGACCCGCGAAGTCAAATGGCCGCACCCAGGAGAAATCCTGATGCAGGAGTGGCTCGAACCCATGGGCCTGAGCCAGTA
CGCGTTGGCAAAGGCCATCGATGTTCCGCCCCGGCGCATCAACGAGATCGTGAAGGGTATGCGCGGCATCACGGCGGATA
CGGCGCTGCGCCTTGCGGTCTTCTTTGGCACGGACGCGCAAAGCTGGCTCAACCTGCAGTCCGACTACGACCTTGCCGAA
GCCCGCGATGCCATGGCGGACGTGCTGGCGCGAATCCAGCGGTTTGAGCCCACGCATCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References