Detailed information of TA system TA217389

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2456944..2457128
• Replicon: chromosome
• Accession: NZ_CP083805
• Organism: Staphylococcus argenteus strain 1801221

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: LB317_RS11860
• Protein ID: WP_000482653.1
• Coordinates: 2457021..2457128 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2456944..2457004 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LB317_RS11850	2452796..2454529	-	1734	WP_031787186.1	ABC transporter ATP-binding protein	-
LB317_RS11855	2454554..2456317	-	1764	WP_031787187.1	ABC transporter ATP-binding protein	-
-	2456944..2457004	+	61	-	-	Antitoxin
LB317_RS11860	2457021..2457128	-	108	WP_000482653.1	type I toxin-antitoxin system Fst family toxin	Toxin
LB317_RS11865	2457262..2457648	-	387	WP_000779346.1	flippase GtxA	-
LB317_RS11870	2457916..2459058	+	1143	WP_031787188.1	glycerate kinase	-
LB317_RS11875	2459117..2459776	+	660	WP_000831306.1	membrane protein	-
LB317_RS11880	2459961..2461172	+	1212	WP_031787189.1	multidrug effflux MFS transporter	-
LB317_RS11885	2461288..2461767	-	480	WP_031787190.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sbi / hlgA / hlgA / hlgC / hlgB	2434742..2457648	22906

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4025.81 Da
• Isoelectric Point: 11.0582

>T217389 WP_000482653.1 NZ_CP083805:c2457128-2457021 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T217389 NZ_CP114200:5555326-5555703 [Streptomyces sp. 71268]
ATGAAGTTCCTGGACCTGCCCCAGTTGCTGGGGCTCGCCCAGCGTCTCGGGGAGAGCGAGGTGCGCGACTACGGATTGCT
GGAGTCCGCACTCGCTCGCCCCCAGGCCAGCGTGTTCGGTCAGGACGCGTACCCCGACGTGTGGCAGAAGGCCGCCGCGC
TGATGGAGTCGCTGGCCCGAAACCACGCCATGGTGGACGGCAACAAGCGCCTCGCCTGGTACGCGACCTGGGTCTTTCTG
CACGTCAATGGCCATCCGCTGGTCGAGGGCTTCGACGTGGACGAGGCCGAGCGCTTCGTCTTGAACGTGGCCCAGGGAGA
GCTGGACGTACCCAAAATCGCGGAATTGCTGCCGCGATTCGCGGCTTCCTCGGCGTAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT217389 NZ_CP083805:2456944-2457004 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin