Detailed information of TA system TA217163

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 179995..180177
• Replicon: chromosome
• Accession: NZ_CP083728
• Organism: Staphylococcus aureus strain MR254

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: K9B11_RS01085
• Protein ID: WP_001801861.1
• Coordinates: 180082..180177 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	179995..180054 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K9B11_RS01070	179133..179510	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
K9B11_RS01075	179704..179880	+	177	Protein_175	transposase	-
K9B11_RS01080	179858..179959	-	102	WP_001791893.1	hypothetical protein	-
-	179995..180054	+	60	-	-	Antitoxin
K9B11_RS01085	180082..180177	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
K9B11_RS01090	180380..180523	+	144	WP_001549059.1	transposase	-
K9B11_RS01095	181127..181510	+	384	WP_000070811.1	hypothetical protein	-
K9B11_RS01100	181521..181697	+	177	WP_000375476.1	hypothetical protein	-
K9B11_RS01105	181699..181884	+	186	WP_000809857.1	hypothetical protein	-
K9B11_RS01110	181998..182639	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
K9B11_RS01115	182857..183408	-	552	WP_000414205.1	hypothetical protein	-
K9B11_RS01120	183506..183850	-	345	WP_000627551.1	DUF3969 family protein	-
K9B11_RS01125	183891..184517	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	161475..206216	44741

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T217163 WP_001801861.1 NZ_CP083728:c180177-180082 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T217163 NZ_CP113936:c21925-21629 [Acinetobacter sp. ESL0695]
ATGATTGAAATTAAACGTCTGCCAGAATTTGATGAATGGCTAGATGGTCTTAAAGACAATATGACCCGAATTCGTTTGAA
TCGCCGATTAGATAAGGTTCAACGTGGCAATTGGGGTGACATTAAGCCACTTCAAGAAGGTGTATGGGAAATGAGAGAGT
TCTTTGGTGCTGGTTGGCGGATGTACTACATCCAACATGGTGACGTTGTGATTGTCATGCTTGGTGGTGGTGAAAAATCT
ACTCAGAGTAAAGACATTGATCGAGCAGTCAAACTGTCGAAAACATTGGAGAATTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT217163 NZ_CP083728:179995-180054 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin