Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1483692..1484209 Replicon chromosome
Accession NZ_CP083648
Organism Corynebacterium coyleae strain FDAARGOS_1492

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1H4NRG6
Locus tag LA324_RS06940 Protein ID WP_070423172.1
Coordinates 1483692..1483952 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LA324_RS06945 Protein ID WP_224213880.1
Coordinates 1483949..1484209 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LA324_RS06920 (LA324_06920) 1479194..1480033 - 840 WP_070451605.1 RecB family exonuclease -
LA324_RS06925 (LA324_06925) 1480060..1481271 + 1212 WP_224212704.1 M18 family aminopeptidase -
LA324_RS06930 (LA324_06930) 1481287..1482120 + 834 WP_224212705.1 tRNA (adenine-N1)-methyltransferase -
LA324_RS06935 (LA324_06935) 1482159..1483682 + 1524 WP_224212706.1 proteasome ATPase -
LA324_RS06940 (LA324_06940) 1483692..1483952 - 261 WP_070423172.1 Txe/YoeB family addiction module toxin Toxin
LA324_RS06945 (LA324_06945) 1483949..1484209 - 261 WP_224213880.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LA324_RS06950 (LA324_06950) 1484287..1485633 - 1347 WP_224212707.1 PLP-dependent aminotransferase family protein -
LA324_RS06955 (LA324_06955) 1485704..1486579 + 876 WP_224212708.1 pyridoxal 5'-phosphate synthase lyase subunit PdxS -
LA324_RS06960 (LA324_06960) 1486637..1488145 + 1509 WP_224212709.1 depupylase/deamidase Dop -
LA324_RS06965 (LA324_06965) 1488162..1488356 + 195 WP_070423179.1 ubiquitin-like protein Pup -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10381.82 Da        Isoelectric Point: 8.0396

>T217022 WP_070423172.1 NZ_CP083648:c1483952-1483692 [Corynebacterium coyleae]
MILSWDEDAWAEYVEWQTTDKRVLKRINMLIRDIQRNGNQGIGKPEPLKHELSGYWSRRITSEHRLVYKMTETEIRIAAC
RYHYGE

Download         Length: 261 bp

>T217022 NZ_CP113540:c2727650-2727547 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9778.97 Da        Isoelectric Point: 4.3246

>AT217022 WP_224213880.1 NZ_CP083648:c1484209-1483949 [Corynebacterium coyleae]
MKVMSYSESRANYAEVLNTVVDDCEEVVITRSGHDPVVIVSLAEYESMKETSYLLQSPANARVLKERIERLEKGTSVQNE
LIEDDR

Download         Length: 261 bp

>AT217022 NZ_CP113540:2727545-2727690 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H4NRG6

Antitoxin

Source ID Structure

References