Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 152611..153204 Replicon chromosome
Accession NC_008344
Organism Nitrosomonas eutropha C91

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag NEUT_RS00775 Protein ID WP_049753074.1
Coordinates 152926..153204 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NEUT_RS00770 Protein ID WP_011633283.1
Coordinates 152611..152916 (-) Length 102 a.a.

Genomic Context

NEUT_RS00745NEUT_RS00750NEUT_RS00755NEUT_RS00765NEUT_RS00780NEUT_RS13455NEUT_RS00770NEUT_RS00775
Location: 148745..149563 (819 bp)
Type: Others
Protein ID: WP_011633279.1
Location: 149712..149915 (204 bp)
Type: Others
Protein ID: WP_049753073.1
Location: 150090..150644 (555 bp)
Type: Others
Protein ID: WP_011633281.1
Location: 151086..152135 (1050 bp)
Type: Others
Protein ID: WP_011633282.1
Location: 153294..154607 (1314 bp)
Type: Others
Protein ID: WP_011633285.1
Location: 154747..158178 (3432 bp)
Type: Others
Protein ID: WP_166484980.1
Location: 152611..152916 (306 bp)
Type: Antitoxin
Protein ID: WP_011633283.1
Location: 152926..153204 (279 bp)
Type: Toxin
Protein ID: WP_049753074.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NEUT_RS00745148745..149563+819WP_011633279.1ABC transporter permease-
NEUT_RS00750149712..149915+204WP_049753073.1hypothetical protein-
NEUT_RS00755150090..150644+555WP_011633281.1ORF6N domain-containing protein-
NEUT_RS00765151086..152135+1050WP_011633282.1Rpn family recombination-promoting nuclease/putative transposase-
NEUT_RS00770152611..152916-306WP_011633283.1HigA family addiction module antidote proteinAntitoxin
NEUT_RS00775152926..153204-279WP_049753074.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NEUT_RS00780153294..154607+1314WP_011633285.1ABC transporter ATP-binding protein-
NEUT_RS13455154747..158178+3432WP_166484980.1glycosyltransferase family 4 protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(25-66)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10529.88 Da        Isoelectric Point: 5.8184

>T21689 WP_049753074.1 NC_008344:c153204-152926 [Nitrosomonas eutropha C91]
MIQSFRCKSTQAVFEGEYPQRFSAIQAAAERKLAQLEAAQTLDFLRSPPGNRLEKLAGDREGQWSIRINAQWRICFTWSD
LGPADVEIVDYH

Download         Length: 279 bp

>T21689 NC_008344:c153204-152926 [Nitrosomonas eutropha C91]
ATGATCCAGTCTTTTCGATGTAAGAGTACGCAAGCAGTGTTTGAGGGTGAATATCCTCAGCGTTTTAGTGCTATCCAAGC
TGCAGCTGAACGTAAGCTGGCACAATTGGAGGCAGCACAAACACTTGATTTTTTGCGTTCTCCACCAGGAAATCGGCTGG
AAAAACTGGCTGGCGACCGGGAAGGTCAATGGAGCATTCGTATCAACGCACAATGGCGTATATGCTTTACTTGGTCTGAT
CTTGGTCCTGCCGATGTAGAGATTGTTGATTATCATTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11402.05 Da        Isoelectric Point: 8.0919

>AT21689 WP_011633283.1 NC_008344:c152916-152611 [Nitrosomonas eutropha C91]
MTRPVNCMRAVHPGEVLREDFLIPAGISVNALAIALSVPATRIHEIVKERRAVTADTAERLAHYFGGDAASWLALQASYD
LKTLPTRDEIERRVQRREEHR

Download         Length: 306 bp

>AT21689 NC_008344:c152916-152611 [Nitrosomonas eutropha C91]
ATGACTAGACCTGTAAACTGCATGCGTGCCGTCCATCCCGGTGAGGTACTGCGTGAAGATTTTTTGATTCCAGCTGGAAT
AAGTGTCAACGCTCTGGCGATTGCCTTGAGTGTGCCAGCCACCCGCATTCATGAAATCGTCAAGGAGCGGCGCGCCGTTA
CCGCTGATACTGCTGAACGGCTGGCGCATTATTTCGGGGGTGATGCTGCTTCCTGGCTTGCTTTGCAGGCCAGCTACGAT
CTGAAAACACTGCCCACGCGCGATGAAATTGAACGCCGCGTGCAAAGACGTGAGGAACACCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References