Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3015929..3016445 Replicon chromosome
Accession NZ_CP083539
Organism Jannaschia sp. W003

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag K3554_RS14950 Protein ID WP_259941669.1
Coordinates 3016179..3016445 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag K3554_RS14945 Protein ID WP_259941667.1
Coordinates 3015929..3016198 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K3554_RS14900 (K3554_14875) 3010986..3011354 - 369 WP_007118848.1 50S ribosomal protein L14 -
K3554_RS14905 (K3554_14880) 3011428..3011658 - 231 WP_259941651.1 30S ribosomal protein S17 -
K3554_RS14910 (K3554_14885) 3011660..3011866 - 207 WP_259941652.1 50S ribosomal protein L29 -
K3554_RS14915 (K3554_14890) 3012240..3012857 - 618 WP_259941653.1 TIGR02466 family protein -
K3554_RS14920 (K3554_14895) 3012954..3013379 - 426 WP_259941655.1 50S ribosomal protein L16 -
K3554_RS14925 (K3554_14900) 3013393..3014130 - 738 WP_259941657.1 30S ribosomal protein S3 -
K3554_RS14930 (K3554_14905) 3014130..3014510 - 381 WP_259941659.1 50S ribosomal protein L22 -
K3554_RS14935 (K3554_14910) 3014516..3014794 - 279 WP_259941662.1 30S ribosomal protein S19 -
K3554_RS14940 (K3554_14915) 3014797..3015639 - 843 WP_259941665.1 50S ribosomal protein L2 -
K3554_RS14945 (K3554_14920) 3015929..3016198 + 270 WP_259941667.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
K3554_RS14950 (K3554_14925) 3016179..3016445 + 267 WP_259941669.1 Txe/YoeB family addiction module toxin Toxin
K3554_RS14955 (K3554_14930) 3016505..3016789 - 285 WP_259941671.1 50S ribosomal protein L23 -
K3554_RS14960 (K3554_14935) 3016786..3017403 - 618 WP_259941673.1 50S ribosomal protein L4 -
K3554_RS14965 (K3554_14940) 3017400..3018278 - 879 WP_259941676.1 50S ribosomal protein L3 -
K3554_RS14970 (K3554_14945) 3018293..3018601 - 309 WP_259941679.1 30S ribosomal protein S10 -
K3554_RS14975 (K3554_14950) 3018781..3019371 - 591 WP_259941681.1 uracil-DNA glycosylase -
K3554_RS14980 (K3554_14955) 3019591..3020766 - 1176 WP_259940969.1 elongation factor Tu -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10541.02 Da        Isoelectric Point: 10.2284

>T216758 WP_259941669.1 NZ_CP083539:3016179-3016445 [Jannaschia sp. W003]
VKLLFADGAWEDYLHWHRTDPKLLRRINDLIREARRTPFDGIGKPEPLRGDLSGWWSRRITREHRMVYRVAGEGDARALE
IAQLRYHY

Download         Length: 267 bp

>T216758 NZ_CP113364:2366694-2366978 [Salmonella enterica subsp. enterica]
ATGACTTATAAGCTGGCATTTAACGAATCTGCACTAAAAGAGTGGAAAAAACTGGGTCATACTATACAGGAACAGTTTAA
AAAAAAGTTACGGGAACGGCTTGAAAACCCTCGGGTTCCGGCTTCTCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGACTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGTGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAGTGACACGACACAGAAGCTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9585.84 Da        Isoelectric Point: 5.6994

>AT216758 WP_259941667.1 NZ_CP083539:3015929-3016198 [Jannaschia sp. W003]
MDIVSYTDARKHLKAVMDRAITDRTETVVTRAGREAVVVVGKEEWDAIQTTLHLLSSPANAARLRAAVGQLDAGGGAERE
LIDGETALR

Download         Length: 270 bp

>AT216758 NZ_CP113364:2366456-2366704 [Salmonella enterica subsp. enterica]
ATGGCATTTCAAATTTTAACGACTACTGCAGCAAGCATTACAGAACTGAAACGTGATCCAATGGGAACTTTCAATGCCGG
AGATGGCGCTCCAGTTGCCATTCTTAACCGTAATGAACCGGCTTTCTACTGTGTGCCTCCGGCACTTTATGCTCATCTTA
TGGATATTCTTGAGGATGAAGAACTCGGTCGTATTATCGATGAGCGTGCGAATGAACGCGTCATTGAGGTCAACATTGAT
GACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References