Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2661081..2661583 Replicon chromosome
Accession NC_008278
Organism Frankia alni ACN14a

Toxin (Protein)


Gene name yoeB Uniprot ID Q0RN04
Locus tag FRAAL_RS10650 Protein ID WP_011603600.1
Coordinates 2661081..2661335 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FRAAL_RS10655 Protein ID WP_041939128.1
Coordinates 2661332..2661583 (-) Length 84 a.a.

Genomic Context

FRAAL_RS10635FRAAL_RS10645FRAAL_RS10660FRAAL_RS10665FRAAL_RS10630FRAAL_RS10640FRAAL_RS10650FRAAL_RS10655
Location: 2657482..2659455 (1974 bp)
Type: Others
Protein ID: WP_041939126.1
Location: 2660266..2661036 (771 bp)
Type: Others
Protein ID: WP_041939127.1
Location: 2661744..2664068 (2325 bp)
Type: Others
Protein ID: WP_011603602.1
Location: 2664068..2665000 (933 bp)
Type: Others
Protein ID: WP_041939129.1
Location: 2656475..2657203 (729 bp)
Type: Others
Protein ID: WP_041940384.1
Location: 2659608..2660060 (453 bp)
Type: Others
Protein ID: WP_011603598.1
Location: 2661081..2661335 (255 bp)
Type: Toxin
Protein ID: WP_011603600.1
Location: 2661332..2661583 (252 bp)
Type: Antitoxin
Protein ID: WP_041939128.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FRAAL_RS106302656475..2657203-729WP_041940384.1GAF domain-containing protein-
FRAAL_RS106352657482..2659455+1974WP_041939126.1PAS domain S-box protein-
FRAAL_RS106402659608..2660060-453WP_011603598.1pyridoxamine 5'-phosphate oxidase family protein-
FRAAL_RS106452660266..2661036+771WP_041939127.1enoyl-CoA hydratase/isomerase family protein-
FRAAL_RS106502661081..2661335-255WP_011603600.1Txe/YoeB family addiction module toxinToxin
FRAAL_RS106552661332..2661583-252WP_041939128.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
FRAAL_RS106602661744..2664068+2325WP_011603602.1FdhF/YdeP family oxidoreductase-
FRAAL_RS106652664068..2665000+933WP_041939129.1formate dehydrogenase accessory sulfurtransferase FdhD-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10302.65 Da        Isoelectric Point: 9.4248

>T21671 WP_011603600.1 NC_008278:c2661335-2661081 [Frankia alni ACN14a]
VKLVWDENAWQDYVWWQTENRKILKRINMLIQDTARNGNDGIGKPEPLKHGFQGYWSRRINDEHRLIYKISDDQIRIAQC
RYHY

Download         Length: 255 bp

>T21671 NC_008278:c2661335-2661081 [Frankia alni ACN14a]
GTGAAGCTCGTCTGGGACGAGAACGCGTGGCAGGACTACGTCTGGTGGCAGACGGAGAACCGTAAAATCCTCAAGCGCAT
CAACATGTTGATCCAGGACACAGCCCGGAACGGCAACGACGGCATCGGCAAGCCCGAACCGCTCAAGCATGGCTTCCAGG
GCTACTGGTCTCGGCGCATCAACGATGAACATCGACTGATCTACAAGATCAGTGACGATCAGATTCGCATAGCCCAGTGC
AGGTACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9249.38 Da        Isoelectric Point: 4.6412

>AT21671 WP_041939128.1 NC_008278:c2661583-2661332 [Frankia alni ACN14a]
VKTMSYSESRARYAEVLTAVADDREEIVITRAGHEPVVIVSLDDYQSLKETAYLLRSPENARRLLAAIDRLENGAGTVRD
LAE

Download         Length: 252 bp

>AT21671 NC_008278:c2661583-2661332 [Frankia alni ACN14a]
GTGAAGACGATGAGCTACTCGGAGTCACGAGCACGCTATGCCGAGGTCCTCACCGCGGTGGCGGACGACCGGGAGGAGAT
CGTCATCACCCGGGCCGGTCACGAGCCGGTCGTCATCGTCTCTCTGGATGACTACCAGTCCCTCAAGGAGACGGCGTACC
TTCTCCGCAGCCCCGAGAACGCCCGCCGGCTGCTGGCCGCCATCGATCGCCTCGAAAACGGCGCCGGCACCGTACGCGAC
CTCGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ0RN04

Antitoxin

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Source
ID
Structure
No matching records found

References