Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 65512..66014 Replicon plasmid unnamed1
Accession NZ_CP083449
Organism Pantoea eucrina strain XL123

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LAC65_RS16465 Protein ID WP_040113377.1
Coordinates 65760..66014 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LAC65_RS16460 Protein ID WP_040113376.1
Coordinates 65512..65763 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LAC65_RS16435 (LAC65_16435) 60729..61307 + 579 WP_040113371.1 TerD family protein -
LAC65_RS16440 (LAC65_16440) 61377..61952 + 576 WP_040113372.1 TerD family protein -
LAC65_RS16445 (LAC65_16445) 62027..63259 + 1233 WP_040113373.1 VWA domain-containing protein -
LAC65_RS16450 (LAC65_16450) 63425..64171 + 747 WP_040113374.1 MerR family transcriptional regulator -
LAC65_RS16455 (LAC65_16455) 64408..65334 + 927 WP_040113375.1 aminoimidazole riboside kinase -
LAC65_RS16460 (LAC65_16460) 65512..65763 + 252 WP_040113376.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
LAC65_RS16465 (LAC65_16465) 65760..66014 + 255 WP_040113377.1 Txe/YoeB family addiction module toxin Toxin
LAC65_RS16470 (LAC65_16470) 66346..67554 + 1209 WP_192415528.1 aldose 1-epimerase family protein -
LAC65_RS16475 (LAC65_16475) 67803..69323 + 1521 WP_040113379.1 carbohydrate porin -
LAC65_RS16480 (LAC65_16480) 69388..70758 + 1371 WP_040113380.1 sucrose-specific PTS transporter subunit IIBC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..107755 107755


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9893.26 Da        Isoelectric Point: 8.8516

>T216470 WP_040113377.1 NZ_CP083449:65760-66014 [Pantoea eucrina]
VKLTWSAEAWEDYLYWQDTDKKTVKKINELIKDASRTPFEGKGKPEPLKHHLAGFWSRRITAEHRLVYAVSDDALLIASC
RYHY

Download         Length: 255 bp

>T216470 NZ_CP113052:2869899-2869994 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9383.64 Da        Isoelectric Point: 4.5983

>AT216470 WP_040113376.1 NZ_CP083449:65512-65763 [Pantoea eucrina]
MKAISYSEARQNLSATMLQTVEDRAPVLITRQNGESCVLMSLEEYNSLEETAYLLRSPKNARRLMDSIESLKSGNGMERD
VIE

Download         Length: 252 bp

>AT216470 NZ_CP113052:c2870081-2870022 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References