Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2219254..2219438 Replicon chromosome
Accession NZ_CP083434
Organism Staphylococcus aureus strain DC.RB_015

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LAE57_RS10550 Protein ID WP_000482647.1
Coordinates 2219254..2219361 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2219378..2219438 (-)

Genomic Context

LAE57_RS10525LAE57_RS10545LAE57_RS10550LAE57_RS10555LAE57_RS10560LAE57_RS10565LAE57_RS10530LAE57_RS10535LAE57_RS10540--
Location: 2214616..2215089 (474 bp)
Type: Others
Protein ID: WP_000456483.1
Location: 2218735..2219121 (387 bp)
Type: Others
Protein ID: WP_000779353.1
Location: 2219254..2219361 (108 bp)
Type: Toxin
Protein ID: WP_000482647.1
Location: 2220009..2221721 (1713 bp)
Type: Others
Protein ID: WP_001064821.1
Location: 2221797..2223530 (1734 bp)
Type: Others
Protein ID: WP_000488493.1
Location: 2223761..2223928 (168 bp)
Type: Others
Protein ID: WP_031845053.1
Location: 2215212..2216423 (1212 bp)
Type: Others
Protein ID: WP_001191921.1
Location: 2216606..2217265 (660 bp)
Type: Others
Protein ID: WP_000831298.1
Location: 2217325..2218467 (1143 bp)
Type: Others
Protein ID: WP_001176863.1
Location: 2219378..2219438 (61 bp)
Type: Antitoxin
Protein ID: -
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LAE57_RS105252214616..2215089+474WP_000456483.1GyrI-like domain-containing protein-
LAE57_RS105302215212..2216423-1212WP_001191921.1multidrug effflux MFS transporter-
LAE57_RS105352216606..2217265-660WP_000831298.1membrane protein-
LAE57_RS105402217325..2218467-1143WP_001176863.1glycerate kinase-
LAE57_RS105452218735..2219121+387WP_000779353.1flippase GtxA-
LAE57_RS105502219254..2219361+108WP_000482647.1type I toxin-antitoxin system Fst family toxinToxin
-2219378..2219438-61--Antitoxin
LAE57_RS105552220009..2221721+1713WP_001064821.1ABC transporter ATP-binding protein-
LAE57_RS105602221797..2223530+1734WP_000488493.1ABC transporter ATP-binding protein-
LAE57_RS105652223761..2223928+168WP_031845053.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T216403 WP_000482647.1 NZ_CP083434:2219254-2219361 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T216403 NZ_CP113039:c781369-781103 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACAATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 61 bp

>AT216403 NZ_CP083434:c2219438-2219378 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A2P7CQJ7

Antitoxin

Download structure file

References