Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4838765..4840022 Replicon chromosome
Accession NZ_CP083387
Organism Arachidicoccus terrestris strain 5GH13-10

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag K9M52_RS18785 Protein ID WP_224069980.1
Coordinates 4838765..4839598 (-) Length 278 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag K9M52_RS18790 Protein ID WP_224069981.1
Coordinates 4839687..4840022 (-) Length 112 a.a.

Genomic Context

K9M52_RS18765K9M52_RS19055K9M52_RS19060K9M52_RS18775K9M52_RS18805K9M52_RS18780K9M52_RS18785K9M52_RS18790K9M52_RS18795K9M52_RS18800K9M52_RS18810K9M52_RS18815
Location: 4835175..4835741 (567 bp)
Type: Others
Protein ID: WP_224069977.1
Location: 4836077..4836589 (513 bp)
Type: Others
Protein ID: WP_262902412.1
Location: 4836601..4837086 (486 bp)
Type: Others
Protein ID: WP_262902413.1
Location: 4837300..4837554 (255 bp)
Type: Others
Protein ID: WP_224069978.1
Location: 4842864..4843547 (684 bp)
Type: Others
Protein ID: WP_224069984.1
Location: 4837930..4838340 (411 bp)
Type: Others
Protein ID: WP_224069979.1
Location: 4838765..4839598 (834 bp)
Type: Toxin
Protein ID: WP_224069980.1
Location: 4839687..4840022 (336 bp)
Type: Antitoxin
Protein ID: WP_224069981.1
Location: 4840395..4840541 (147 bp)
Type: Others
Protein ID: WP_224069982.1
Location: 4840948..4841913 (966 bp)
Type: Others
Protein ID: WP_224069983.1
Location: 4843571..4844185 (615 bp)
Type: Others
Protein ID: WP_224069985.1
Location: 4844294..4844773 (480 bp)
Type: Others
Protein ID: WP_224069986.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K9M52_RS18765 (K9M52_18780)4835175..4835741+567WP_224069977.1hypothetical protein-
K9M52_RS19055 (K9M52_18785)4836077..4836589+513WP_262902412.1PD-(D/E)XK nuclease family transposase-
K9M52_RS19060 (K9M52_18790)4836601..4837086+486WP_262902413.1Rpn family recombination-promoting nuclease/putative transposase-
K9M52_RS18775 (K9M52_18795)4837300..4837554+255WP_224069978.1hypothetical protein-
K9M52_RS18780 (K9M52_18800)4837930..4838340-411WP_224069979.1glyoxalase/bleomycin resistance/extradiol dioxygenase family protein-
K9M52_RS18785 (K9M52_18805)4838765..4839598-834WP_224069980.1HipA domain-containing proteinToxin
K9M52_RS18790 (K9M52_18810)4839687..4840022-336WP_224069981.1HipA N-terminal domain-containing proteinAntitoxin
K9M52_RS18795 (K9M52_18815)4840395..4840541-147WP_224069982.1RagB/SusD family nutrient uptake outer membrane protein-
K9M52_RS18800 (K9M52_18820)4840948..4841913-966WP_224069983.1hypothetical protein-
K9M52_RS18805 (K9M52_18825)4842864..4843547+684WP_224069984.1type 1 glutamine amidotransferase domain-containing protein-
K9M52_RS18810 (K9M52_18830)4843571..4844185-615WP_224069985.1SRPBCC domain-containing protein-
K9M52_RS18815 (K9M52_18835)4844294..4844773-480WP_224069986.1SRPBCC domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(21-241)

Antitoxin

HipA, N-terminal subdomain 1

(6-102)


Sequences

Toxin        


Download         Length: 278 a.a.        Molecular weight: 31695.64 Da        Isoelectric Point: 8.5870

>T216339 WP_224069980.1 NZ_CP083387:c4839598-4838765 [Arachidicoccus terrestris]
MELDQEKLNILAQFIVHERMAITGVQPKISLILNGEKGNKRLTSVGLWGDYILKPDTADFPCVPEVEDLTMHLAALFNIE
TAKHALIPTSTGQLAYITKRFDRQKGKKIHTEDLCQLSELLTEQKYKSSYERVGKLIRQYATNSGLVVIQYFRLVLFSFL
TGNNDMHLKNFSLVHTEKGILIAPAYDLLNVNLVYPEDKEDLALTLGGRKRKIKRSDVDLFAQNIGIANPVRDNIYKEFA
RCAKQVDDWIERSFLTDAYKENYSSIVTRKLKQIDLL

Download         Length: 834 bp

>T216339 NZ_CP113016:c2847925-2847773 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAAAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12713.53 Da        Isoelectric Point: 4.8498

>AT216339 WP_224069981.1 NZ_CP083387:c4840022-4839687 [Arachidicoccus terrestris]
MARQAKIYFQGNLAGYLVEGDNGYSFQYSLEYLAMKDAKPISLTLPLSEKTYHSNVLFPFFDGLIPEGWLLEIGEKHWKL
NPRDRFELLINLCRDTVGAVAVYPVEAETHE

Download         Length: 336 bp

>AT216339 NZ_CP113016:c2848549-2847950 [Staphylococcus aureus]
ATGGCAATGAACTTTAAAGTCTTTGACAATAGTCAACTTGTAGCAGAATATGCTGCTGATATTATTAGAAAGCAATTTAA
CAATAATCCTACTACAATTGCAGGTTTTCATTTAGATACGGATCAAGCGCCAGTTCTAGATGAATTAAAGAAAAATGTTG
AAAAATATGCTGTTGATTTTAGCCAAATAAATATTTTAGATTATGACGATAAAAAATCATATTTCGAAGCGTTAGGTGTA
CCAGCAGGTCAAGTTTATCCAATTGCTTATGAAAAAGATGCAATCGAATTAATCGCTGATAAGATTAAAACTAAAGAAAA
TAAAGGGAAATTAACATTACAAGTTGTTTCTATCGATGAGCAAGGTAAGTTAAATGTTAGTATTCGTCAAGGACTAATGG
AAGCAAGAGAAATTTTCTTAGTAGTGACAGGTGCTAATAAACGAGATGTAGTTGAAAAATTATATCAAGAAAATGGTAAA
ACAAGCTTCGAACCAGCCGATTTAAAAGCACATAGAATGGTAAATGTTATTCTTGATAAAGAAGCGGCTGCAGGTTTACC
TGAAGATGTTAAAGCTTACTTTACGTCACGCTTTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References