Detailed information of TA system TA021633

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 3814359..3814581
• Replicon: chromosome
• Accession: NC_008253
• Organism: Escherichia coli 536

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: ECP_RS26495
• Protein ID: WP_001295224.1
• Coordinates: 3814359..3814466 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	3814515..3814581 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ECP_RS18520	3809612..3810364	-	753	WP_000279537.1	cellulose biosynthesis protein BcsQ	-
ECP_RS18525	3810376..3810564	-	189	WP_001063314.1	YhjR family protein	-
ECP_RS18530	3810837..3812408	+	1572	WP_001204945.1	cellulose biosynthesis protein BcsE	-
ECP_RS18535	3812405..3812596	+	192	WP_000988313.1	cellulose biosynthesis protein BcsF	-
ECP_RS18540	3812593..3814272	+	1680	WP_000191565.1	cellulose biosynthesis protein BcsG	-
ECP_RS26495	3814359..3814466	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	3814515..3814581	+	67	-	-	Antitoxin
ECP_RS18555	3814942..3816213	+	1272	WP_001298005.1	amino acid permease	-
ECP_RS18560	3816243..3817247	-	1005	WP_000103577.1	dipeptide ABC transporter ATP-binding subunit DppF	-
ECP_RS18565	3817244..3818227	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
ECP_RS18570	3818238..3819140	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T21633 WP_001295224.1 NC_008253:c3814466-3814359 [Escherichia coli 536]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T21633 NC_008253:c3814466-3814359 [Escherichia coli 536]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT21633 NC_008253:3814515-3814581 [Escherichia coli 536]
GTCTAGGTTCAAGATTAGCCCCCGTGGTATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin