Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 4493291..4493511 | Replicon | chromosome |
Accession | NZ_CP083273 | ||
Organism | Escherichia coli strain BL21-RIPL |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | J7R083 |
Locus tag | K9U36_RS21920 | Protein ID | WP_000170963.1 |
Coordinates | 4493291..4493398 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 4493445..4493511 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K9U36_RS21895 | 4488971..4489648 | + | 678 | Protein_4299 | RHS repeat-associated core domain-containing protein | - |
K9U36_RS21900 | 4489648..4489974 | + | 327 | WP_000873944.1 | protein YbfB | - |
K9U36_RS21905 | 4490076..4491088 | - | 1013 | Protein_4301 | IS3-like element IS150 family transposase | - |
K9U36_RS21910 | 4491136..4492170 | + | 1035 | Protein_4302 | glutamate decarboxylase | - |
K9U36_RS21915 | 4492109..4493200 | - | 1092 | Protein_4303 | elongation factor Tu | - |
K9U36_RS21920 | 4493291..4493398 | - | 108 | WP_000170963.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- | 4493445..4493511 | + | 67 | - | - | Antitoxin |
K9U36_RS21925 | 4493826..4493933 | - | 108 | WP_000170963.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- | 4493981..4494046 | + | 66 | NuclAT_17 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_17 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_17 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_17 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_20 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_20 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_20 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_20 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_23 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_23 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_23 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_23 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_26 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_26 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_26 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_26 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_29 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_29 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_29 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_29 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_32 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_32 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_32 | - | - |
- | 4493981..4494046 | + | 66 | NuclAT_32 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_35 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_35 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_35 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_35 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_38 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_38 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_38 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_38 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_41 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_41 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_41 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_41 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_44 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_44 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_44 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_44 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_47 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_47 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_47 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_47 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_50 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_50 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_50 | - | - |
- | 4493981..4494048 | + | 68 | NuclAT_50 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_53 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_53 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_53 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_53 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_56 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_56 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_56 | - | - |
- | 4493982..4494047 | + | 66 | NuclAT_56 | - | - |
K9U36_RS21930 | 4494270..4494377 | - | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
K9U36_RS21935 | 4494753..4494860 | - | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
K9U36_RS21940 | 4495117..4495814 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
K9U36_RS21945 | 4495830..4496477 | + | 648 | Protein_4309 | RHS element protein | - |
K9U36_RS22135 | 4496469..4496603 | + | 135 | Protein_4310 | serum resistance lipoprotein Bor | - |
K9U36_RS22140 | 4496635..4497135 | - | 501 | WP_263300663.1 | prophage endopeptidase RzpD | - |
K9U36_RS21965 | 4497086..4497514 | - | 429 | Protein_4312 | ISAs1 family transposase | - |
K9U36_RS21970 | 4497717..4497836 | + | 120 | Protein_4313 | IS3 family transposase | - |
K9U36_RS21975 | 4497934..4498086 | + | 153 | WP_000956455.1 | type I toxin-antitoxin system toxin HokE | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | tufA | 4476659..4496937 | 20278 | |
- | inside | IScluster/Tn | - | tufA | 4473015..4497514 | 24499 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3971.74 Da Isoelectric Point: 11.4779
>T216258 WP_000170963.1 NZ_CP083273:c4493398-4493291 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK
Download Length: 108 bp
>T216258 NZ_CP112997:c2198444-2198148 [Mycobacterium tuberculosis variant bovis]
GTGAGTAGCCGATACCTTCTCTCGCCTGCCGCGCAGGCACATCTGGAAGAGATCTGGGACTGCACCTATGACCGTTGGGG
TGTCGATCAGGCCGAGCAGTACCTGCGCGAACTTCAACACGCTATCGACCGTGCTGCGGCAAACCCGCGGATCGGACGAG
CGTGCGACGAGATTCGCCCCGGCTATCGCAAGCTCTCGGCCGGGTCACACACGTTGTTCTATCGGGTGACTGGCGAAGGC
ACCATCGACGTCGTGCGAGTCCTGCACCAACGGATGGACGTCGACCGGAACCTCTGA
GTGAGTAGCCGATACCTTCTCTCGCCTGCCGCGCAGGCACATCTGGAAGAGATCTGGGACTGCACCTATGACCGTTGGGG
TGTCGATCAGGCCGAGCAGTACCTGCGCGAACTTCAACACGCTATCGACCGTGCTGCGGCAAACCCGCGGATCGGACGAG
CGTGCGACGAGATTCGCCCCGGCTATCGCAAGCTCTCGGCCGGGTCACACACGTTGTTCTATCGGGTGACTGGCGAAGGC
ACCATCGACGTCGTGCGAGTCCTGCACCAACGGATGGACGTCGACCGGAACCTCTGA
Antitoxin
Download Length: 67 bp
>AT216258 NZ_CP083273:4493445-4493511 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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