Detailed information of TA system TA215596

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2069482..2069728
• Replicon: chromosome
• Accession: NZ_CP082924
• Organism: Bacillus subtilis strain FJAT-4

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: K8U58_RS10355
• Protein ID: WP_109789044.1
• Coordinates: 2069482..2069574 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2069555..2069728 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K8U58_RS10340	2064641..2064976	+	336	WP_009967409.1	hypothetical protein	-
K8U58_RS10345	2065023..2068628	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
K8U58_RS10350	2068861..2069193	-	333	WP_026009814.1	hypothetical protein	-
K8U58_RS10355	2069482..2069574	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2069555..2069728	-	174	-	-	Antitoxin
K8U58_RS10360	2069843..2070685	-	843	WP_003231327.1	hypothetical protein	-
K8U58_RS10365	2070885..2071343	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
K8U58_RS10370	2071353..2073155	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
K8U58_RS10375	2073257..2073814	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2048132..2080693	32561

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T215596 WP_109789044.1 NZ_CP082924:2069482-2069574 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T215596 NZ_CP110817:161596-161745 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT215596 NZ_CP082924:c2069728-2069555 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin