Detailed information of TA system TA215192

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2292868..2293084
• Replicon: chromosome
• Accession: NZ_CP082815
• Organism: Staphylococcus aureus strain SCAID WND1-2021 (598)

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: K8B78_RS11420
• Protein ID: WP_073392962.1
• Coordinates: 2292980..2293084 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2292868..2292923 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K8B78_RS11400	2287961..2288281	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
K8B78_RS11405	2288283..2289263	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
K8B78_RS11410	2289529..2290620	+	1092	WP_000495684.1	hypothetical protein	-
K8B78_RS11415	2290908..2292554	+	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2292868..2292923	+	56	-	-	Antitoxin
K8B78_RS11420	2292980..2293084	-	105	WP_073392962.1	hypothetical protein	Toxin
K8B78_RS11425	2293764..2293922	+	159	WP_001792784.1	hypothetical protein	-
K8B78_RS11430	2294581..2295438	-	858	WP_000370937.1	HAD family hydrolase	-
K8B78_RS11435	2295506..2296288	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2290908..2292554	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-121)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T215192 WP_073392962.1 NZ_CP082815:c2293084-2292980 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T215192 NZ_CP110532:45952-46350 [Enterobacter roggenkampii]
ATGAGACATATGCTGGATACGAATATTGTGAGTCACTTGTTTAAACGACACCCGGAGGTTGTAAGCAGAATGACATGTCT
GGCGCCGGGTGACGTTTGTATCTCAAGCATTACCGAAGCGGAATTGCTGTATGGTGCTGACAAGAAGAAAAGCAGTAGAT
TGAAAGAAACAATCCGGGAGTTTCTCAATACCATCACGATTTGCGACTGGGACAGCGACGCCGCAGCAACGTACGGTGAA
CTCCGTGCAACCCTGGAAAAGAAAGGGAAAGTGATGGGGGATCTCGATCAACTGATCGCTGCACATGCTATCAGTCGGGG
AACAACGATCGTTACTAACGATCGTGCATTCAGAATGGTGCAGGAGCTTGCCGTCGAGGACTGGACGACAACGTTGTGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT215192 NZ_CP082815:2292868-2292923 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin