Detailed information of TA system TA215180

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1871240..1871420
• Replicon: chromosome
• Accession: NZ_CP082815
• Organism: Staphylococcus aureus strain SCAID WND1-2021 (598)

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: K8B78_RS08825
• Protein ID: WP_001801861.1
• Coordinates: 1871240..1871335 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1871363..1871420 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K8B78_RS08795	1866384..1867010	+	627	WP_000669038.1	hypothetical protein	-
K8B78_RS08800	1867051..1867395	+	345	WP_000627550.1	DUF3969 family protein	-
K8B78_RS08805	1867493..1868065	+	573	WP_000414222.1	hypothetical protein	-
K8B78_RS08810	1868214..1869581	-	1368	WP_001093574.1	FRG domain-containing protein	-
K8B78_RS08815	1869581..1870150	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
K8B78_RS08820	1870343..1870789	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
K8B78_RS08825	1871240..1871335	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1871363..1871420	-	58	-	-	Antitoxin
K8B78_RS08830	1871458..1871559	+	102	WP_001791232.1	hypothetical protein	-
K8B78_RS08835	1871734..1872177	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
K8B78_RS08840	1872177..1872620	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
K8B78_RS08845	1872620..1873061	-	442	Protein_1751	DUF1433 domain-containing protein	-
K8B78_RS08850	1873586..1876006	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T215180 WP_001801861.1 NZ_CP082815:1871240-1871335 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T215180 NZ_CP082815:1871240-1871335 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT215180 NZ_CP082815:c1871420-1871363 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin