Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2502533..2502717 Replicon chromosome
Accession NC_007795
Organism Staphylococcus aureus subsp. aureus NCTC 8325

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SAOUHSC_02721 Protein ID YP_501184.1
Coordinates 2502610..2502717 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2502533..2502593 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAOUHSC_A02577 2498063..2498230 - 168 YP_501179.1 hypothetical protein -
SAOUHSC_02717 2498230..2498373 - 144 YP_501180.1 hypothetical protein -
SAOUHSC_02718 2498461..2500194 - 1734 YP_501181.1 hypothetical protein -
SAOUHSC_02719 2500219..2501982 - 1764 YP_501182.1 hypothetical protein -
SAOUHSC_02720 2502476..2502583 - 108 YP_501183.1 hypothetical protein -
- 2502533..2502593 + 61 - - Antitoxin
SAOUHSC_02721 2502610..2502717 - 108 YP_501184.1 hypothetical protein Toxin
SAOUHSC_02722 2502851..2503237 - 387 YP_501185.1 hypothetical protein -
SAOUHSC_02723 2503505..2504647 + 1143 YP_501186.1 glycerate kinase -
SAOUHSC_02724 2504707..2505366 + 660 YP_501187.1 hypothetical protein -
SAOUHSC_02725 2505548..2506759 + 1212 YP_501188.1 hypothetical protein -
SAOUHSC_02726 2506882..2507355 - 474 YP_501189.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T21496 YP_501184.1 NC_007795:c2502717-2502610 [Staphylococcus aureus subsp. aureus NCTC 8325]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T21496 NC_007795:c2502717-2502610 [Staphylococcus aureus subsp. aureus NCTC 8325]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT21496 NC_007795:2502533-2502593 [Staphylococcus aureus subsp. aureus NCTC 8325]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q2FVI9

Antitoxin

Download structure file

References