Detailed information of TA system TA021482

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 942257..942475
• Replicon: chromosome
• Accession: NC_007795
• Organism: Staphylococcus aureus subsp. aureus NCTC 8325

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: Q2FZN4
• Locus tag: SAOUHSC_00966
• Protein ID: YP_499519.1
• Coordinates: 942257..942364 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	942359..942475 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAOUHSC_00961	938930..939460	-	531	YP_499514.1	hypothetical protein	-
SAOUHSC_00962	939709..939927	+	219	YP_499515.1	hypothetical protein	-
SAOUHSC_00963	940008..940994	-	987	YP_499516.1	lipoyltransferase and lipoate-protein ligase	-
SAOUHSC_00964	941193..941369	+	177	YP_499517.1	hypothetical protein	-
SAOUHSC_00965	941384..941986	+	603	YP_499518.1	hypothetical protein	-
SAOUHSC_00966	942257..942364	+	108	YP_499519.1	hypothetical protein	Toxin
-	942359..942475	-	117	-	-	Antitoxin
SAOUHSC_00967	942903..943004	+	102	YP_499520.1	hypothetical protein	-
SAOUHSC_00968	943330..945294	+	1965	YP_499521.1	hypothetical protein	-
SAOUHSC_00969	945297..945617	+	321	YP_499522.1	hypothetical protein	-
SAOUHSC_00970	945614..946255	+	642	YP_499523.1	ABC transporter ATP-binding protein	-
SAOUHSC_00971	946343..946633	-	291	YP_499524.1	hypothetical protein	-
SAOUHSC_00972	946912..947199	+	288	YP_499525.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3788.69 Da
• Isoelectric Point: 10.8004

>T21482 YP_499519.1 NC_007795:942257-942364 [Staphylococcus aureus subsp. aureus NCTC 8325]
VISIANALHLMLSFGMFIVTFIGIVVAIINLSNKK

Nucleotide

• Length: 108 bp

>T21482 NC_007795:942257-942364 [Staphylococcus aureus subsp. aureus NCTC 8325]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTATAGTAGTAGC
AATAATAAATTTAAGCAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 117 bp

>AT21482 NC_007795:c942475-942359 [Staphylococcus aureus subsp. aureus NCTC 8325]
TGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACC
ATCATTCTATGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Toxin

• AlphaFold DB: Q2FZN4

Antitoxin