21475

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2265084..2265347 Replicon chromosome
Accession NC_007793
Organism Staphylococcus aureus subsp. aureus USA300 FPR3757

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAUSA300_RS11570 Protein ID WP_001802298.1
Coordinates 2265243..2265347 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2265084..2265248 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAUSA300_RS11550 2261267..2261932 - 666 WP_001024094.1 SDR family oxidoreductase -
SAUSA300_RS11555 2262084..2262404 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAUSA300_RS11560 2262406..2263386 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SAUSA300_RS11565 2263652..2264743 + 1092 WP_000495671.1 lytic regulatory protein -
- 2265084..2265248 + 165 - - Antitoxin
SAUSA300_RS11570 2265243..2265347 - 105 WP_001802298.1 hypothetical protein Toxin
SAUSA300_RS15820 2265508..2265991 - 484 Protein_2201 recombinase family protein -
SAUSA300_RS11580 2266034..2267170 - 1137 WP_000115564.1 SAP domain-containing protein -
SAUSA300_RS11585 2267459..2267551 + 93 WP_001790138.1 hypothetical protein -
SAUSA300_RS11590 2268256..2269113 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SAUSA300_RS11595 2269181..2269963 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T21475 WP_001802298.1 NC_007793:c2265347-2265243 [Staphylococcus aureus subsp. aureus USA300_FPR3757]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T21475 NC_007793:c2265347-2265243 [Staphylococcus aureus subsp. aureus USA300_FPR3757]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT21475 NC_007793:2265084-2265248 [Staphylococcus aureus subsp. aureus USA300_FPR3757]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References