Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 87076..87897 Replicon plasmid p4_CQ10
Accession NZ_CP082296
Organism Pantoea agglomerans strain CQ10

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag K6R05_RS21245 Protein ID WP_222925809.1
Coordinates 87076..87546 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag K6R05_RS21250 Protein ID WP_161736173.1
Coordinates 87553..87897 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6R05_RS21235 (K6R05_21235) 82411..84813 + 2403 WP_222925807.1 maltodextrin phosphorylase -
K6R05_RS21240 (K6R05_21240) 84822..86888 + 2067 WP_222925808.1 4-alpha-glucanotransferase -
K6R05_RS21245 (K6R05_21245) 87076..87546 - 471 WP_222925809.1 type II toxin-antitoxin system YhaV family toxin Toxin
K6R05_RS21250 (K6R05_21250) 87553..87897 - 345 WP_161736173.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
K6R05_RS21255 (K6R05_21255) 87996..88211 - 216 WP_222925810.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
K6R05_RS21260 (K6R05_21260) 88401..89333 - 933 WP_222925811.1 maltose operon protein MalM -
K6R05_RS21265 (K6R05_21265) 89432..90733 - 1302 WP_222925812.1 maltoporin -
K6R05_RS21270 (K6R05_21270) 90777..91886 - 1110 WP_150015485.1 maltose/maltodextrin ABC transporter ATP-binding protein MalK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..137838 137838


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

SpoVT-AbrB domain

(16-54)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 18308.83 Da        Isoelectric Point: 8.9277

>T214536 WP_222925809.1 NZ_CP082296:c87546-87076 [Pantoea agglomerans]
MEDSTVINGWHVYVHPCFESQLIALTNEVELLRAKYPESYQRKATTKLLAAVFKVINSEICTDPHQAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKTIILAWMNDAETKRAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWANTNS

Download         Length: 471 bp

>T214536 NZ_CP110130:1126976-1127257 [Methylorubrum extorquens]
ATGATCCTCAGCTACCGCAACAGGGGCACCGAAGCGCTGGACGTGCACGGTGTGTGCCATCGCCGCTGGCGGTCCTTTCA
AGCTGCGGCCGGGCGCAAGCTCGATATGCTGAACGCCGCCTCCGTCGTGAGCGACCTGCGCAGCCCGCCCGGCAACCGTC
TGGAGAAGCTGTCGGGTGATCGCGAGGGCCAGTGGAGCATCCGCATCAACGATCAATGGCGCATCTGCTTCCGATGGGAC
GGTTCGGGGCCCGAGGATGTCGAGATTGTCGATTATCACTGA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12255.93 Da        Isoelectric Point: 4.3278

>AT214536 WP_161736173.1 NZ_CP082296:c87897-87553 [Pantoea agglomerans]
MGTLTHANISLRASSKLTARSQTTIPAAVRDAMNLQPGENIEYAVLPGGKVLIARQETVTDDDPVMASFLSFLAADIRNT
PANIKTLDRGLLTRITSLTEGMDVDLDAPLMDDE

Download         Length: 345 bp

>AT214536 NZ_CP110130:1127271-1127555 [Methylorubrum extorquens]
ATGCCTCGCATTAGATCTCATCCGGGCGAGATCCTGCTCGAAGAATACCTTCGACCCCTGGAAATGAGCGCCAACGCTCT
GGCGAAGGCGATCGAGGTGCCAGCCAACCGCATCAGCGAACTTCTGCGCGGTCGCCGCGGGATGACCGCCGACACGGCCT
GCCGCCTCGGCCGGTTCTTCGGGACCACGCCGGAATTCTGGATGAGTCTCCAGACCGCCCACGATCTGTCGAGGGCCGTC
GCGGAGCACGACTATTCCACCTTGCGTGCTCTCGAAAGCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References