Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 128224..128726 Replicon plasmid p2_CQ10
Accession NZ_CP082294
Organism Pantoea agglomerans strain CQ10

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag K6R05_RS20105 Protein ID WP_161736637.1
Coordinates 128472..128726 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag K6R05_RS20100 Protein ID WP_222925667.1
Coordinates 128224..128475 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6R05_RS20085 (K6R05_20085) 123955..125409 + 1455 WP_222925666.1 flagellin -
K6R05_RS20090 (K6R05_20090) 125747..127060 + 1314 WP_161736640.1 CitMHS family transporter -
K6R05_RS20095 (K6R05_20095) 127226..128065 + 840 WP_161736639.1 MBL fold metallo-hydrolase -
K6R05_RS20100 (K6R05_20100) 128224..128475 + 252 WP_222925667.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
K6R05_RS20105 (K6R05_20105) 128472..128726 + 255 WP_161736637.1 Txe/YoeB family addiction module toxin Toxin
K6R05_RS20110 (K6R05_20110) 128800..131337 - 2538 WP_222925668.1 excinuclease ABC subunit UvrA -
K6R05_RS20115 (K6R05_20115) 131558..131950 - 393 WP_222925669.1 transcriptional regulator -
K6R05_RS20120 (K6R05_20120) 131950..132051 - 102 WP_260059782.1 type II toxin-antitoxin system HigB family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..160986 160986


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9900.25 Da        Isoelectric Point: 8.8485

>T214534 WP_161736637.1 NZ_CP082294:128472-128726 [Pantoea agglomerans]
VKLTWSEETWEDYLYWQDTDKKTVKKINELLKDASRTPFEGKGKPEPLKHNLAGFWSRRITAEHRLVYAVSGDALLIASC
RYHY

Download         Length: 255 bp

>T214534 NZ_CP110128:6177208-6177486 [Pseudomonas sp. WJP1]
ATGATCAGATCCTTTCAGCACAAAGGCCTTCGTGGCTTCTATGAAACAGGTTCGACTCGGGGAATTCGCGCAGATCATGC
GAAACGTCTGGGGCGTATGCTGCAATTCATGGATCGCGCAGCGGTACCCGGCGACCTCGACCTTCCAGGGTGGCGGTTAC
ATCCCCTCAAGGGAGAGTTGGCCGAGTACTGGTCACTGACCGTTTCCGGAAACTGGCGGGTCATTTTTCGATTTACCGGA
TCGGATATCGAACTGGTCGACTATCTGGACTATCACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9320.43 Da        Isoelectric Point: 4.4143

>AT214534 WP_222925667.1 NZ_CP082294:128224-128475 [Pantoea agglomerans]
MRAISYSEARQNLSATMVQTVEDKAPVLITRQNGESCVLMSLEEYNSLEETAYLLRSPKNAHRLMDSIESLQSGNGTDRD
IIE

Download         Length: 252 bp

>AT214534 NZ_CP110128:6177500-6177787 [Pseudomonas sp. WJP1]
ATGCCCATGCACAACCCGCCGCACCCTGGCGAAACACTGTTGATGGATGTATTGCCTGAACTGGGCATCAGCGTCGCAGA
ACTCGCCCGGCACCTTGGGTTTGCGCGCCCGCATCTGTCGCGGGTGCTGCATGGACATGCACCAGTCAGTCCCGATTTGG
CCGTGCGTTTGGAACGCGCAGGGATCGGCAAGGCCCGCATGTGGTTAGGGGTACAGACCGATTATGATCTGTGGCAAGCG
GAGCAGCGTGAGCAACCGCCCATCAAACCCATCGCCGCTCACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References