Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1531534..1532194 Replicon chromosome
Accession NZ_CP082292
Organism Pantoea agglomerans strain CQ10

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag K6R05_RS07090 Protein ID WP_222925288.1
Coordinates 1531534..1531887 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag K6R05_RS07095 Protein ID WP_033733169.1
Coordinates 1531892..1532194 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6R05_RS07075 (K6R05_07075) 1527137..1527418 + 282 WP_135908208.1 hypothetical protein -
K6R05_RS07080 (K6R05_07080) 1527572..1529734 - 2163 WP_222925287.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
K6R05_RS07085 (K6R05_07085) 1530160..1531248 + 1089 WP_161736888.1 YncE family protein -
K6R05_RS07090 (K6R05_07090) 1531534..1531887 + 354 WP_222925288.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K6R05_RS07095 (K6R05_07095) 1531892..1532194 + 303 WP_033733169.1 XRE family transcriptional regulator Antitoxin
K6R05_RS07105 (K6R05_07105) 1532864..1533787 + 924 WP_033733168.1 sugar ABC transporter substrate-binding protein -
K6R05_RS07110 (K6R05_07110) 1533820..1535304 + 1485 WP_098052921.1 sugar ABC transporter ATP-binding protein -
K6R05_RS07115 (K6R05_07115) 1535328..1536353 + 1026 WP_190285965.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-79)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13644.75 Da        Isoelectric Point: 10.0341

>T214528 WP_222925288.1 NZ_CP082292:1531534-1531887 [Pantoea agglomerans]
VWMIKTTERFDRWFTLLNDSDRACVLAALMVLREKGPGLSRPYADTIKGSAYINMKELRIQSRGDPIRAFYAFDPNRTAI
VLCAGNKAGNEKRFYREMLPVADREFTHWLKSFNHKE

Download         Length: 354 bp

>T214528 NZ_CP110128:c2640288-2640019 [Pseudomonas sp. WJP1]
ATGCGGGTTGAGTGGCGTCCCGAGGCACGATCCGATCTGTTGCAAATCCTCAATTACATTGGTGACCGTAATCTCGTAGC
GGCTCTGGCGCTCAACCAGGCCATTGAAACGGCTACATCAGCTCTCCCCGAACATCCCTATCTCTATCGATGTGGCCGAC
TTACCGGTACGCGAGAAATTGTTGTGCATCCCAATTACCTGGTGGTCTATCGGGTGACGGATCAAATCCAGATCCTGAGC
GTGTTACATGCCAGGCAGGAATACCCCTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10911.69 Da        Isoelectric Point: 5.7134

>AT214528 WP_033733169.1 NZ_CP082292:1531892-1532194 [Pantoea agglomerans]
MGRTLEQLIADEKPEVVADAQAMATEILLNIHLAELREKVQKTQVEMAQALGITQPTVAGMEKPGRDLKLSTLKRYVDAA
GGKLRLVVELPDGSHYGFVV

Download         Length: 303 bp

>AT214528 NZ_CP110128:c2640469-2640278 [Pseudomonas sp. WJP1]
ATGAACGTCCGATTTTCCTCCATAGTTTCAGAATTTGAAACCGCAGAGCAGGCTACCCGCTACGACCGCTGGTTCCGTGC
CAAGGTACAGGCATCCCTGGATGATCCGCGCCCAAGCATCCCGCATGATCAAGTGATGGCTGAAATGCGAGCCCTCCTGG
AGTCAAAGCGCAACAAGCGCGATGCGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References