Detailed information of TA system TA214490

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrG/-
• Location: 2203431..2203681
• Replicon: chromosome
• Accession: NZ_CP082279
• Organism: Bacillus amyloliquefaciens strain Bam1

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: K7I17_RS11170
• Protein ID: WP_009967548.1
• Coordinates: 2203431..2203547 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrG
Locus tag	-
Coordinates	2203542..2203681 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K7I17_RS11140 (2198550)	2198550..2198828	+	279	WP_014470075.1	hypothetical protein	-
K7I17_RS11145 (2199025)	2199025..2200142	+	1118	Protein_2167	tetratricopeptide repeat protein	-
K7I17_RS11150 (2200306)	2200306..2201556	-	1251	WP_014470073.1	UV-damage repair protein uvrX	-
K7I17_RS11155 (2201549)	2201549..2201881	-	333	WP_014470072.1	YolD-like family protein	-
K7I17_RS11160 (2202100)	2202100..2202872	-	773	Protein_2170	sporulation protein YunB	-
K7I17_RS11165 (2202999)	2202999..2203202	-	204	WP_014470071.1	hypothetical protein	-
K7I17_RS11170 (2203431)	2203431..2203547	+	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
- (2203542)	2203542..2203681	-	140	NuclAT_0	-	Antitoxin
- (2203542)	2203542..2203681	-	140	NuclAT_0	-	Antitoxin
- (2203542)	2203542..2203681	-	140	NuclAT_0	-	Antitoxin
- (2203542)	2203542..2203681	-	140	NuclAT_0	-	Antitoxin
K7I17_RS11175 (2203855)	2203855..2204313	-	459	WP_014470070.1	YrhA family protein	-
K7I17_RS11180 (2204326)	2204326..2206212	-	1887	WP_014470069.1	T7SS effector LXG polymorphic toxin	-
K7I17_RS11185 (2206719)	2206719..2207489	+	771	WP_014470068.1	hypothetical protein	-
K7I17_RS11190 (2207533)	2207533..2207967	-	435	WP_076982859.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2062632..2211003	148371

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T214490 WP_009967548.1 NZ_CP082279:2203431-2203547 [Bacillus amyloliquefaciens]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T214490 NZ_CP110117:656279-656593 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin

Nucleotide

• Length: 140 bp

>AT214490 NZ_CP082279:c2203681-2203542 [Bacillus amyloliquefaciens]
AAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCACCCCGGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCG
ATGTTGAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin