Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3388572..3389278 Replicon chromosome
Accession NZ_CP082269
Organism Enterobacter sp. C2

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag K4042_RS16485 Protein ID WP_222888711.1
Coordinates 3388976..3389278 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag K4042_RS16480 Protein ID WP_222888710.1
Coordinates 3388572..3388973 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K4042_RS16455 3383821..3384144 - 324 WP_222888705.1 DUF3561 family protein -
K4042_RS16460 3384192..3384797 - 606 WP_222888706.1 adenylyl-sulfate kinase -
K4042_RS16465 3384797..3386224 - 1428 WP_222888707.1 sulfate adenylyltransferase subunit CysN -
K4042_RS16470 3386234..3387142 - 909 WP_222888708.1 sulfate adenylyltransferase subunit CysD -
K4042_RS16475 3387441..3388487 + 1047 WP_222888709.1 aminopeptidase -
K4042_RS16480 3388572..3388973 - 402 WP_222888710.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
K4042_RS16485 3388976..3389278 - 303 WP_222888711.1 type II toxin-antitoxin system MqsR family toxin Toxin
K4042_RS16490 3389591..3389926 - 336 WP_222888712.1 HigA family addiction module antitoxin -
K4042_RS16495 3390422..3390877 - 456 WP_286184757.1 lysozyme inhibitor LprI family protein -
K4042_RS16500 3391027..3391761 - 735 WP_144817747.1 phosphoadenosine phosphosulfate reductase -
K4042_RS16505 3391859..3393571 - 1713 WP_222888713.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(3-99)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11318.23 Da        Isoelectric Point: 10.0980

>T214477 WP_222888711.1 NZ_CP082269:c3389278-3388976 [Enterobacter sp. C2]
MGEKWTPHTRLHIVKTMVRAGKVRTTISAYNGAAALGFKSRIEMYGAVLALAPSDFYKSMTADKDPGYWQEVYRLVYNGQ
SIYLKLIVKDNVVIVSFKEL

Download         Length: 303 bp

>T214477 NZ_CP110102:c3176944-3176636 [Serratia marcescens]
ATGCAGTTTACCGTATATGACAATACGTATCCGGCATCAGCCTATCCCTACTTACTGGACGTTCAAAGCGATCTTATTGA
TGCCCTCTCGACCCGGTTAATGATCCCTCTTTATGCTTTGGATAACGTCAGAGTTAAAATTTCTGCACGCCTGTGCCCGG
AGATTGAGGTAAACGGCGAAAAGTTTCTCGTTATGACCCATGAGATGGCAGCCGTACGTATTTCACAGATCGGGAAGGCC
GTTGGTAATGCCAATGAGCACAGGAATCAAATTAAAGCTGCCATCGATTTTCTGATTGATGGCTTTTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14780.70 Da        Isoelectric Point: 5.7949

>AT214477 WP_222888710.1 NZ_CP082269:c3388973-3388572 [Enterobacter sp. C2]
MKCPGCGGADLKHETRNVEYEYKGRKTTVYGITGDYCDACGESILDDEAGDTYMAAIGAFNREVNAQEVDPAFIARIRKR
FKLDQRQAAEIFGGGANAFSRYETGRVAPPRPLVLLFKALDKHPEIFEELKQA

Download         Length: 402 bp

>AT214477 NZ_CP110102:c3177183-3176947 [Serratia marcescens]
ATGGCAAATAACAATGTGACGAAAAAGACAGTCAACGTAACCATCGATCGCGATCTTTTCCAGCGTGCAAAATCCCTGGG
CGTTAATGTGTCATCCGTATTGACAGACGCATTGAGCGTCCGTGTCAGGGATATTGAGATTCAACAGTGGCGCGAGCAAA
ATCGCGCGGCGTTAGAAGAACTTAATCGCATCACTGAAGAAAATGGTTTGTTGTCTGATGAATATCGGACATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References